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Benzene and naphthalene in air and breath as indicators of exposure to jet fuel.

机译：空气和呼吸中的苯和萘是飞机燃料暴露的指标。

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AIMS: To estimate exposures to benzene and naphthalene among military personnel working with jet fuel (JP-8) and to determine whether naphthalene might serve as a surrogate for JP-8 in studies of health effects. METHODS: Benzene and naphthalene were measured in air and breath of 326 personnel in the US Air Force, who had been assigned a priori into low, moderate, and high exposure categories for JP-8. RESULTS: Median air concentrations for persons in the low, moderate, and high exposure categories were 3.1, 7.4, and 252 microg benzene/m3 air, 4.6, 9.0, and 11.4 microg benzene/m3 breath, 1.9, 10.3, and 485 microg naphthalene/m3 air, and 0.73, 0.93, and 1.83 microg naphthalene/m3 breath, respectively. In the moderate and high exposure categories, 5% and 15% of the benzene air concentrations, respectively, were above the 2002 threshold limit value (TLV) of 1.6 mg/m3. Multiple regression analyses of air and breath levels revealed prominent background sources of benzene exposure, including cigarette smoke. However, naphthalene exposure was not unduly influenced by sources other than JP-8. Among heavily exposed workers, dermal contact with JP-8 contributed to air and breath concentrations along with several physical and environmental factors. CONCLUSIONS: Personnel having regular contact with JP-8 are occasionally exposed to benzene at levels above the current TLV. Among heavily exposed workers, uptake of JP-8 components occurs via both inhalation and dermal contact. Naphthalene in air and breath can serve as useful measures of exposure to JP-8 and uptake of fuel components in the body.
机译：目的：评估使用喷气燃料（JP-8）的军事人员在苯和萘中的暴露，并确定在健康影响研究中萘是否可以替代JP-8。方法：对美国空军中326名人员的空气和呼吸中的苯和萘进行了测量，这些人员已被优先分配给JP-8低，中和高暴露类别。结果：低，中和高暴露类别人员的空气中位数浓度为3.1、7.4和252微克苯/立方米空气，4.6、9.0和11.4微克苯/立方米呼吸，1.9、10.3和485微克萘。 / m3空气，分别为0.73、0.93和1.83 microg萘/ m3呼吸。在中度和高度暴露类别中，苯空气浓度分别为5％和15％，高于2002年的阈值限值（TLV）1.6 mg / m3。空气和呼吸水平的多元回归分析显示了苯暴露的主要背景来源，包括香烟烟雾。但是，除了JP-8以外，萘的暴露并没有受到不适当的影响。在暴露严重的工人中，与JP-8的皮肤接触会导致空气和呼吸的浓度升高以及一些物理和环境因素。结论：经常与JP-8接触的人员偶尔会暴露于高于当前TLV的水平的苯中。在接触严重的工人中，通过吸入和皮肤接触会吸收JP-8成分。空气和呼吸中的萘可作为暴露于JP-8和吸收体内燃料成分的有用措施。

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