...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Occupational and environmental medicine >Moulds, bacteria and cancer among Finns: an occupational cohort study.
【24h】

Moulds, bacteria and cancer among Finns: an occupational cohort study.

机译：芬兰人中的霉菌，细菌和癌症：一项职业队列研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Some environmental moulds and bacteria produce carcinogenic toxins. AIM: To study associations between work-related exposure to moulds and bacteria and cancers in Finland. METHODS: A cohort of all economically active Finns in the population census in 1970 were followed-up for 30 million person-years. Subsequent cancer cases were identified through record linkage with the Finnish Cancer Registry. Observed and expected numbers of cancer cases were calculated by occupation, sex, birth cohort and period of observation. Exposures to moulds of agricultural and industrial origin and to bacteria of non-human origin were estimated with the Finnish Job-Exposure Matrix. RESULTS: Men with the highest mould and bacterial exposure had a reduced relative risk for lung cancer (RR 0.7, 95% CI 0.6 to 0.9 for moulds and RR 0.9, 95% CI 0.8 to 1.0 for bacteria). Women in the highest mould and bacterial exposure category had RRs of 3.1 (95% CI 1.0 to 9.2) and 2.6 (95% CI 1.5 to 4.7) for cervical cancer, respectively. The respective RRs for lip cancer were 2.4 (95% CI 1.2 to 5.1) and 1.6 (95% CI 1.2 to 2.2). CONCLUSIONS: Exposures at the investigated concentrations to either moulds or bacteria are unlikely to be major risk factors of cancer, although suggestions of risk increases were observed for some cancer types. It has been suggested previously that the decreased risk for lung cancer is due to the protective effect of endotoxins.
机译：背景：一些环境霉菌和细菌会产生致癌毒素。目的：研究与工作有关的霉菌暴露与细菌和癌症之间的联系。方法：对1970年人口普查中所有从事经济活动的芬兰人进行了随访，随访时间为3000万人年。通过与芬兰癌症登记处的记录联系确定了随后的癌症病例。通过职业，性别，出生队列和观察期来计算观察和预期的癌症病例数。用芬兰工作暴露矩阵估算了农业和工业来源的霉菌和非人类来源的细菌的暴露。结果：霉菌和细菌暴露量最高的男性患肺癌的相对风险降低（霉菌的RR 0.7，95％CI 0.6到0.9，细菌的RR 0.9，95％CI 0.8到1.0）。霉菌和细菌暴露类别最高的女性宫颈癌的RRs分别为3.1（95％CI 1.0至9.2）和2.6（95％CI 1.5至4.7）。唇癌的RR分别为2.4（95％CI 1.2至2.2）和1.6（95％CI 1.2至2.2）。结论：尽管观察到某些类型癌症的风险增加的提示，但在研究浓度下的霉菌或细菌暴露不太可能是癌症的主要危险因素。先前已经提出，降低的肺癌风险是由于内毒素的保护作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号