...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Occupational and environmental medicine >Long-term air pollution exposure and risk factors for cardiovascular diseases among the elderly in Taiwan.
【24h】

Long-term air pollution exposure and risk factors for cardiovascular diseases among the elderly in Taiwan.

机译：台湾老年人的长期空气污染暴露和心血管疾病的危险因素。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES: To investigate changes in blood pressure, blood lipids, blood sugar and haematological markers of inflammation associated with changes in long-term exposure to ambient air pollutants. METHODS: We conducted secondary analyses of data on blood pressure and blood biochemistry markers from the Social Environment and Biomarkers of Aging Study in Taiwan and air pollution data from the Taiwan Environmental Protection Administration in 2000. Associations of 1-year averaged criteria air pollutants (particulate matter with aerodynamic diameters <10 mum (PM(10)) and <2.5 mum (PM(2.5)), ozone (O(3)), nitrogen dioxide (NO(2)), sulfur dioxide and carbon monoxide) with systolic blood pressure, diastolic blood pressure, total cholesterol, triglycerides, high-density lipoprotein cholesterol, fasting glucose, haemoglobin A1c (HbA1c), interleukin 6 (IL-6) and neutrophils were explored by applying generalised additive models. RESULTS: After controlling for potential confounders, we observed that increased 1-year averaged particulate air pollutants (PM(10) and PM(2.5)) and NO(2) were associated with elevated blood pressure, total cholesterol, fasting glucose, HbA1c, IL-6 and neutrophils. Associations of increased 1-year averaged O(3) with elevated blood pressure, total cholesterol, fasting glucose, HbA1c and neutrophils were also observed. In particular, our two-pollutant models showed that PM(2.5) was more significantly associated with end-point variables than two gaseous pollutants, O(3) and NO(2). CONCLUSIONS: Changes in blood pressure, blood lipids, blood sugar and haematological markers of inflammation are associated with long-term exposure to ambient air pollutants. This might provide a link between air pollution and atherosclerotic cardiovascular diseases.
机译：目的：研究与长期暴露于环境空气污染物中的变化有关的血压，血脂，血糖和炎症的血液学指标的变化。方法：我们对台湾的社会环境和衰老研究的生物标志物的血压和血液生化标志物的数据以及台湾环境保护局在2000年的空气污染数据进行了二次分析。1年平均标准的空气污染物协会（微粒空气动力学直径<10毫米（PM（10））和<2.5毫米（PM（2.5）），臭氧（O（3）），二氧化氮（NO（2）），二氧化硫和一氧化碳的物质血压，舒张压，总胆固醇，甘油三酸酯，高密度脂蛋白胆固醇，空腹血糖，血红蛋白A1c（HbA1c），白介素6（IL-6）和中性粒细胞通过应用广义加性模型进行了研究。结果：控制了潜在的混杂因素后，我们观察到1年平均颗粒空气污染物（PM（10）和PM（2.5））和NO（2）的增加与血压升高，总胆固醇，空腹血糖，HbA1c， IL-6和中性粒细胞。还观察到与升高的血压，总胆固醇，空腹血糖，HbA1c和中性粒细胞相关的1年平均O（3）增加。特别是，我们的两种污染物模型显示，与两种气体污染物O（3）和NO（2）相比，PM（2.5）与终点变量的关联更为显着。结论：血压，血脂，血糖和炎症的血液学指标的变化与长期暴露于环境空气污染物有关。这可能在空气污染和动脉粥样硬化性心血管疾病之间建立联系。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号