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首页> 外文期刊>Occupational and environmental medicine >Medication use in relation to noise from aircraft and road traffic in six European countries: results of the HYENA study.
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Medication use in relation to noise from aircraft and road traffic in six European countries: results of the HYENA study.

机译：在六个欧洲国家，与飞机和道路交通产生的噪音有关的药物使用：HYENA研究的结果。

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OBJECTIVES: Studies on the health effects of aircraft and road traffic noise exposure suggest excess risks of hypertension, cardiovascular disease and the use of sedatives and hypnotics. Our aim was to assess the use of medication in relation to noise from aircraft and road traffic. METHODS: This cross-sectional study measured the use of prescribed antihypertensives, antacids, anxiolytics, hypnotics, antidepressants and antasthmatics in 4,861 persons living near seven airports in six European countries (UK, Germany, the Netherlands, Sweden, Italy, and Greece). Exposure was assessed using models with 1 dB resolution (5 dB for UK road traffic noise) and spatial resolution of 250x250 m for aircraft and 10x10 m for road traffic noise. Data were analysed using multilevel logistic regression, adjusting for potential confounders. RESULTS: We found marked differences between countries in the effect of aircraft noise on antihypertensive use; for night-time aircraft noise, a 10 dB increase in exposure was associated with ORs of 1.34 (95% CI 1.14 to 1.57) for the UK and 1.19 (1.02 to 1.38) for the Netherlands but no significant associations were found for other countries. For day-time aircraft noise, excess risks were found for the UK (OR 1.35; CI: 1.13 to 1.60) but a risk deficit for Italy (OR 0.82; CI: 0.71 to 0.96). There was an excess risk of taking anxiolytic medication in relation to aircraft noise (OR 1.28; CI: 1.04 to 1.57 for daytime and OR 1.27; CI: 1.01 to 1.59 for night-time) which held across countries. We also found an association between exposure to 24hr road traffic noise and the use of antacids by men (OR 1.39; CI 1.11 to 1.74). CONCLUSION: Our results suggest an effect of aircraft noise on the use of antihypertensive medication, but this effect did not hold for all countries. Results were more consistent across countries for the increased use of anxiolytics in relation to aircraft noise.
机译：目的：对飞机和道路交通噪声的健康影响的研究表明，高血压，心血管疾病以及使用镇静剂和催眠药的风险较高。我们的目的是评估与飞机和道路交通噪音有关的药物使用情况。方法：这项横断面研究测量了居住在六个欧洲国家（英国，德国，荷兰，瑞典，意大利和希腊）的七个机场附近的4,861人中使用的处方降压药，抗酸药，抗焦虑药，催眠药，抗抑郁药和麻醉药的使用情况。使用具有1 dB分辨率（英国道路交通噪声为5 dB），飞机的空间分辨率为250x250 m，道路交通噪声为10x10 m的模型评估暴露。使用多级逻辑回归分析数据，调整潜在的混杂因素。结果：我们发现各国之间飞机噪声对降压使用的影响存在明显差异;对于夜间飞机噪声，英国的OR值为1.34（95％CI为1.14至1.57），荷兰的OR为1.19（1.02至1.38），其暴露增加10 dB，但其他国家未发现明显的相关性。对于日间飞机噪声，英国的风险较高（OR 1.35; CI：1.13至1.60），而意大利则存在风险赤字（OR 0.82; CI：0.71至0.96）。与飞机噪音有关的服用抗焦虑药的风险很高（白天在OR为1.28; CI在夜间为1.04至1.57，夜间在OR为1.27; CI在1.01至1.59之间）。我们还发现，暴露于24小时道路交通噪音与男性使用抗酸剂之间存在关联（OR 1.39; CI 1.11至1.74）。结论：我们的结果表明飞机噪声对降压药的使用有影响，但这种影响并非在所有国家都有效。各国在与飞机噪声有关的抗焦虑药使用方面的结果在各个国家更为一致。

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