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Trends in maternal deaths from epilepsy in the United Kingdom: a 30-year retrospective review

机译:英国癫痫病孕妇死亡趋势:30年回顾性回顾

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Objective: Neurological diseases remain the second most common cause of maternal mortality from indirect causes, according to the last United Kingdom confidential enquiry into maternal death. The maternal mortality rate from epilepsy is reported as 0.61 per 100,000 maternities. The aim of this study was to analyse the trends and causes of maternal death from epilepsy in the UK over the last 30 years. Information on sub-standard care associated with fatalities was also consolidated to inform guidance and clinical care by obstetricians and physicians caring for pregnant women with epilepsy. Study design: A retrospective review of 10 triennial confidential enquiry into maternal death reports (1979-2008) was performed, encompassing 21,514,457 maternities. Late and coincidental deaths were not included in the analyses. Results: Between 1979 and 2008, there were 92 maternal deaths from epilepsy. The proportion of total maternal deaths from epilepsy over 30 years is 3.7% (95% Cl 3.0—4.5), which showed an increasing trend. Sudden unexpected death in epilepsy remains the single greatest cause of maternal death from epilepsy followed by aspiration of gastric contents during seizures and drowning during bathing. Conclusion: All women with epilepsy should be looked after by specialist combined obstetric and medical or neurological teams in pregnancy to improve maternal and fetal outcomes.
机译:目的:根据上次英国对孕产妇死亡的秘密调查,神经病仍然是由间接原因引起的孕产妇死亡的第二大最常见原因。据报告,癫痫病的孕产妇死亡率为每十万名妇女0.61。这项研究的目的是分析过去30年来英国癫痫病致死的趋势和原因。还整合了与死亡相关的不合标准的护理信息,以指导妇科医生和护理癫痫孕妇的临床护理。研究设计:回顾性审查了10个三年期对孕产妇死亡报告的机密询问(1979-2008年),涉及21,514,457例患儿。分析中未包括晚期和偶然死亡。结果:1979年至2008年之间,有92名孕妇死于癫痫病。 30年来,由癫痫病造成的孕产妇死亡总比例为3.7%(95%Cl 3.0-4.5),呈上升趋势。癫痫突然猝死仍然是孕妇癫痫发作死亡的最大原因,癫痫发作期间有胃内容物吸入,洗澡时溺水淹死。结论:妊娠期间所有癫痫妇女均应由产科和医学或神经科专家小组共同护理,以改善母婴结局。

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