Allergic responses to a variety of seafood have been described, including fish. We report the evaluation of a 31-year-old worker who developed occupational asthma following exposure to sole fish (Yellotvfin sole). She had been working in a restaurant's kitchen, cooking different types of products including fish, most often sole. In the last 3 years, this worker had developed erythema and pruritus of the hands and forearms while she was manipulating fishes such as sole. In the month before being assessed at our Centre, she had increasing symptoms of dyspnoea, chest tightness and wheezing when she was exposed to cooking fumes from sole fish. She also reported symptoms suggestive of localised angioedema developing when she was eating fish. She had no nocturnal respiratory symptoms. She had used inhaler salbutamol on a PRN basis, taken usually up to twice a day most of the days, montelukast 10 mg daily, nasal saline and she also had been given injectable epineghrine on demand, although she never used it. She had smoked about 10 cigarettes per day since the age of 18
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