ROS in the aging male: model diseases with ROS-related pathophysiology.

Angelopoulou R; Lavranos G; Manolakou P

首页> 外文期刊>Reproductive toxicology >ROS in the aging male: model diseases with ROS-related pathophysiology.

【24h】

ROS in the aging male: model diseases with ROS-related pathophysiology.

机译：老年男性中的ROS：具有ROS相关病理生理学的疾病模型。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The aging process is a complex biological phenomenon that can be attributed to several mechanisms. ROS (reactive oxygen species) activity is widely considered one of them, as it is associated with extensive damage in a variety of cells. For example, the gradual decrease in fertility often accompanying aging males can be traced back to oxidative stress, since ROS are released throughout life from the mitochondrial respiratory chain. Cumulative intracellular damage as a result of the increased ROS concentration affects all tissues that perform aerobic metabolism and, owing to blood circulation, anaerobic tissues as well. Naturally, other mechanisms such as cell inflammation and lack or incapacity of antioxidant enzymes also contribute to the variety of systematic distortions that characterize aging. Finally, the particularly elevated number of adult men that show, among others, a gradual deterioration in reproductive functions suggests a central role of ROS generation in senescence in general and male aging, in particular.

机译：衰老过程是一种复杂的生物学现象，可以归因于多种机制。 ROS（活性氧）活性被广泛认为是其中之一，因为它与多种细胞的广泛损伤有关。例如，经常伴随衰老的男性生育力的逐渐下降可以追溯到氧化应激，因为ROS是从线粒体呼吸链中释放出来的。 ROS浓度升高导致的细胞内累积损伤会影响所有进行有氧代谢的组织，并且由于血液循环也会影响厌氧组织。自然地，其他机制，例如细胞炎症和抗氧化酶的缺乏或丧失能力，也导致了表征衰老的各种系统畸变。最后，特别是成年男性数量的增加尤其显示出生殖功能的逐渐恶化，这表明ROS的产生在一般的，尤其是男性衰老的衰老中起着核心作用。

著录项

来源
《Reproductive toxicology》 |2009年第2期|共5页
作者
Angelopoulou R; Lavranos G; Manolakou P;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学;
关键词

相似文献

外文文献
中文文献
专利

1. ROS in the aging male: model diseases with ROS-related pathophysiology. [J] . Angelopoulou R, Lavranos G, Manolakou P Reproductive toxicology . 2009,第2期

机译：老年男性中的ROS：具有ROS相关病理生理学的疾病模型。
2. Daily chronomics of proteomic profile in aging and rotenone-induced Parkinson's disease model in male Wistar rat and its modulation by melatonin [J] . Jagota Anita, Mattam Ushodaya Biogerontology . 2017,第4期

机译：老化和旋转酮诱导帕金森病患帕金森病的每日编音学术治疗雄性Wistar大鼠的疾病模型及其褪黑素调节
3. Daily chronomics of proteomic profile in aging and rotenone-induced Parkinson's disease model in male Wistar rat and its modulation by melatonin [J] . Jagota Anita, Mattam Ushodaya Biogerontology . 2017,第4期

机译：蛋白质组学概况的日常编音学在衰老和旋转龙诱导的帕金森病疾病模型中的雄性Wistar大鼠及其褪黑素调节
4. Role of testosterone in resistance to development of stress-related vascular diseases in male and female organisms: models of hypertension and ulcer bleeding [C] . O. Semyachkina-Glushkovskaya, A. Pavlov, I. Semyachkin-Glushkovskiy, Saratov fall meeting . 2015

机译：睾酮在雄性和雌性生物中应力相关血管疾病发展抗性的作用：高血压和溃疡出血模型
5. From Single Cells to Human Disease: High-Resolution Phenotyping of Male Infertility Models Using Single-Cell RNA Sequencing [D] . Jung, Min. 2019

机译：从单细胞到人类疾病：使用单细胞RNA测序的男性不孕症模型的高分辨率表型
6. Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. [O] . C K Goldman, J Kim, W L Wong, 1993

机译：表皮生长因子刺激人恶性神经胶质瘤细胞产生血管内皮生长因子：多形性胶质母细胞瘤病理生理模型。
7. Effect of dehydroepiandrosterone on ovarian morphology and follicular apoptosis following 4-vinylcyclohexene diepoxide induced premature follicle loss in rats Original Article March 2020 259 Views Aim: Chemical-induced depletion of ovarian follicle pool can lead to premature ovarian failure in rats. In the rat model of 4-vinylcyclohexene diepoxide (VCD)- induced ovarian follicular loss, we tested the hypothesis that Dehydroepiandrosterone (DHEA) could be reversed by short and long-term treatment of follicular loss. Material and Method: All rats were divided into groups for study and treated with dimethylsulfoxide… Additional Info Recieved 13.01.2019 Accepted 13.02.2019 Published Online 19.02.2019 Printed 01.03.2020 DOI 10.4328/ACAM.6163 Author Mehmet Caner Özer, Mehmet Kaya, Ahmet Berkız Turp, Cengiz Bal, Nilüfer Erkasap, Didem Turgut Coşan, Hikmet Hassa Identifier Corresponding Author ORCID ID: https://orcid.org/ 0000-0002-4398-9598 Index Page 104-110 Citations in Google Scholar Google Scholar How to Cite Özer MC, Kaya M, Turp AB, Bal C, Erkasap N, Coşan DT, Hassa H. Effect of dehydroepiandrosterone on ovarian morphology and follicular apoptosis following 4-vinylcyclohexene diepoxide induced premature follicle loss in rats. Ann Clin Anal Med 2020;11(2):104-110 Running Title Dehydroepiandrosterone and premature ovarian loss in a rat model Download attachments: 10.4328ACAM.6163.pdf Read more... Late onset hirayama disease: Characteristic magnetic resonance imaging features hirayana disease Case Report March 2020 346 Views Hirayama Disease is a rare benign lower motor neuron disorder which is primarily affecting young males. It is characterized by the progressive weakness of the distal upper extremities followed by spontaneous stabilization of the symptoms. In this paper, we describe a 58 year- old female patient with a complaint of weakness in the right hand and forearm. Magnetic resonance imaging… Additional Info Recieved 09.01.2019 Accepted 25.01.2019 Published Online 05.02.2019 Printed 01.03.2020 DOI 10.4328/ACAM.6154 Author Kemal Murat Haberal, Aynur Yılmaz Avcı, Mert Bayramoğlu, Ahmet Muhteşem Ağıldere Identifier Corresponding Author ORCID ID: https://orcid.org/0000-0002-8211-4065 Index Page 159-161 Citations in Google Scholar Google Scholar How to Cite Haberal KM, Avcı AY, Bayramoğlu M, Ağıldere AM. Late onset hirayama disease: Characteristic magnetic resonance imaging features hirayana disease. Ann Clin Anal Med 2020;11(2): 159-161 Running Title Hirayama disease Download attachments: 10.4328ACAM.6154.pdf Read more... The relationship between serum vitamin D levels and dry eye syndrome in postmenopausal women [O] . Ayşegül Arman 2020

机译：脱氢卓酮对卵巢形态和卵泡细胞凋亡后的4-乙烯基环己肽诱导大鼠早产权损失的影响原文2020年3月2020年3月2020年3月观点：卵巢卵巢池的化学诱导耗尽会导致大鼠过早的卵巢衰竭。在4-乙烯基环己肽二极管（VCD）诱导的卵巢卵泡损失的大鼠模型中，我们测试了脱氢贫康松（DHEA）可以通过短期和长期治疗卵泡损失来逆转的假设。材料和方法：将所有大鼠分为研究和用二甲基磺砜进行研究的组......附加信息13.01.2019已接受13.02.2019在线发布19.02.2019印刷01.03.2020 Doi 10.4328 / Acam.6163作者Mehmet CanerÖzer，Mehmet Kaya，Mehmet Kaya， AhmetBerkızTutp，Cengiz Bal，NilüferERKASAP，Didem TurgutCoşan，Hikmet Hassa标识符相应作者Orcid ID：https：///orcid.org/0000-0002-4398-9598索引Page 104-110谷歌学者谷歌学者如何CITEÖZERMC，KAYA M，TURP AB，BAL C，ERKASAP N，Coşandt，哈萨甘酮，脱氢贫康松对卵巢形态和卵泡细胞凋亡的影响在4-乙烯基环己肽诱导的大鼠过早卵泡损失之后。 Ann Clin Anal Med 2020; 11（2）：104-110在大鼠模型下载附件中运行脱氢脱氢睾酮和过早的卵巢损失：10.4328ACAM.6163.PDF阅读更多...延迟发作Hirayama病：特征磁共振成像特征Hirayana疾病案例报告3月2020年3月346意见Hirayama疾病是一种罕见的良性降低运动神经元障碍，主要是影响年轻男性。它的特征在于远端上肢的渐进弱点，然后是自发稳定的症状。在本文中，我们描述了一个58岁的女性患者，右手和前臂抱怨弱点。磁共振成像......额外信息收到09.01.2019已接受25.01.2019在线发布05.02.2019印刷品01.03.2020 Doi 10.4328 / Acam.6154作者Kemal Murat Haberal，AynurYılmazavcı，MertBayramoğlu，AhmetMuhteşemAğıldere标识符相应的作者Orcid ID： https://orcid.org/0000-0002-8211-4065 expert page 159-161谷歌学者谷歌学者如何引用Haberal km，avcıay，bayramoğlum，ağıldeream。晚期起源亨拉山疾病：特征磁共振成像特征Hirayana病。 Ann Clin Anal Med 2020; 11（2）：159-161运行标题Hirayama疾病下载附件：10.4328CAM.6154.PDF阅读更多...绝经后血清维生素D水平和干眼症综合征的关系

ROS in the aging male: model diseases with ROS-related pathophysiology.

摘要

著录项

相似文献

相关主题

期刊订阅