...
首页> 外文期刊>Reproductive toxicology >Infection with Parvovirus B19 and Herpes viruses in early pregnancy and risk of second trimester miscarriage or very preterm birth.
【24h】

Infection with Parvovirus B19 and Herpes viruses in early pregnancy and risk of second trimester miscarriage or very preterm birth.

机译:早孕期感染细小病毒B19和疱疹病毒,并有中期妊娠流产或早产的风险。

获取原文
获取原文并翻译 | 示例
           

摘要

We investigated whether infections with Parvovirus B19 and Herpes viruses in early pregnancy increase risks of second trimester miscarriage or delivery before 32 gestational weeks. Blood samples taken in early pregnancy were analyzed for Parvovirus B19 or Herpes viruses. Viremia was found in blood samples of 11 (4.7%) women with second trimester miscarriage and 10 (3.7%) women with very preterm birth, compared to 5 (1.7%) women who delivered at term, corresponding to adjusted odds ratios [95% CI] of 3.32 [0.93, 11.8] and 2.21 [0.71, 6.84], respectively. In stratified analyses, Parvovirus B19 viremia was associated with adjusted odds ratios of 3.76 [0.77, 18.3] for second trimester miscarriage and 2.66 [0.64, 11.1] for very preterm birth. Corresponding odds ratios for Human Herpes virus 6 viremia was 2.52 [0.33, 19.5] and 1.08 [0.14, 8.08], respectively. In conclusion, this study lends some support to the hypothesis that women with viremia in early pregnancy may face an increased risk of second trimester miscarriage or very preterm birth. Studies with larger sample sizes are needed.
机译:我们调查了怀孕初期细小病毒B19和疱疹病毒的感染是否会增加孕中期流产或在妊娠32周之前分娩的风险。对怀孕初期的血液样本进行细小病毒B19或疱疹病毒分析。在11例(4.7%)早孕妇女和10例(3.7%)早产妇女的血液样本中发现病毒血症,相比之下,足月分娩的5例(1.7%)妇女,对应于调整后的优势比[95% CI分别为3.32 [0.93,11.8]和2.21 [0.71,6.84]。在分层分析中,细小病毒B19病毒血症与早孕流产的调整比值比为3.76 [0.77,18.3],极早产为2.66 [0.64,11.1]。人疱疹病毒6病毒血症的相应比值比分别为2.52 [0.33,19.5]和1.08 [0.14,8.08]。总而言之,这项研究为以下假设提供了一定的支持,即早孕期病毒血症的妇女可能会出现早孕或早产的风险增加。需要进行更大样本量的研究。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号