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首页> 外文期刊>Reproductive toxicology >Early pregnancy blood lead levels and the risk of premature rupture of the membranes.
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Early pregnancy blood lead levels and the risk of premature rupture of the membranes.

机译：怀孕早期的血铅水平和胎膜早破的风险。

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摘要

To clarify the effects of lead on fetal premature rupture of the membranes (PROM), blood lead concentrations were measured using inductively coupled plasma-mass spectrometry in 332 women, aged 16-35 years, during their early pregnancy period (8-12 weeks). Blood lead concentrations were significantly higher in the 36 PROM deliveries than in the 296 non-PROM deliveries (mean +/- SD, 4.61 +/- 2.37 and 3.69 +/- 1.85 mug/dl, respectively; p<0.05). The logistic regression analysis revealed that a 1-unit increase in the logarithm of the blood lead level led to a several-fold increase in the risk of PROM (unit risk=17.98, 95% CI 1.6-198.6). Thus, it is suggested that lead can increase the risk of PROM in pregnant women with mean blood lead less than 5 mug/dl.
机译：为了阐明铅对胎儿胎膜早破的影响，使用电感耦合等离子体质谱法测定了332名年龄在16-35岁的孕妇在怀孕初期（8-12周）的血铅浓度。 。 36胎PROM的血铅浓度显着高于296胎非PROM的血铅浓度（分别为+/- SD，4.61 +/- 2.37和3.69 +/- 1.85 mug / dl; p <0.05）。 Logistic回归分析显示，血铅水平的对数增加1个单位会导致PROM风险增加几倍（单位风险= 17.98，95％CI 1.6-198.6）。因此，建议铅可增加平均血液铅含量低于5杯/分升的孕妇发生PROM的风险。

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