States of water adsorbed on perindopril crystals

Stepanov V.A.; Khmelevskaya V.S.; Bogdanov N.Yu.; Gorchakov K.A.

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States of water adsorbed on perindopril crystals

机译：培哚普利晶体上吸附的水的状态

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The relationship between the structural state of adsorbed water, the crystal structure of the substances, and the solubility of the perindopril salt C_(19)H_(32)N_2O_5 · C4H11N in water was studied by IR spectroscopy and X-ray diffractometry. The high-frequency shift of the stretching vibrations of adsorbed water and the solubility depend on the crystal structure of the drug substance. A reversible chemical reaction occurred between the adsorbed water and the perindopril salt. nds, structural polymorphism, dissolution.

机译：通过红外光谱和X射线衍射法研究了吸附水的结构状态，物质的晶体结构与培哚普利盐C_（19）H_（32）N_2O_5·C4H11N在水中的溶解度之间的关系。吸附水的拉伸振动的高频位移和溶解度取决于药物的晶体结构。吸附的水和培哚普利盐之间发生可逆的化学反应。 nds，结构多态性，溶解。

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《Russian Journal of Physical Chemistry》 |2011年第10期|共4页
作者
Stepanov V.A.; Khmelevskaya V.S.; Bogdanov N.Yu.; Gorchakov K.A.;
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正文语种 eng
中图分类物理化学（理论化学）、化学物理学;
关键词
Dissolution; Organic molecular compounds; Structural polymorphism;

机译：溶解;有机分子化合物;结构多态性;

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专利

1. States of water adsorbed on perindopril crystals [J] . Stepanov V.A., Khmelevskaya V.S., Bogdanov N.Yu., Russian Journal of Physical Chemistry . 2011,第10期

机译：培哚普利晶体上吸附的水的状态
2. Electric-field-dependent empirical potentials for molecules and crystals: A first application to flexible water molecule adsorbed in zeolites [J] . Cicu P., Spanu S., Suffritti GB., The Journal of Chemical Physics . 2000,第19期

机译：分子和晶体的电场相关经验势：分子筛中吸附的柔性水分子的首次应用
3. Electric-field-dependent empirical potentials for molecules and crystals: A first application to flexible water molecule adsorbed in zeolites [J] . Cicu P., Spanu S., Suffritti GB., The Journal of Chemical Physics . 2000,第19期

机译：分子和晶体的电场相关经验势：分子筛中吸附的柔性水分子的首次应用
4. The ionization and desorption energies of silver adsorbed on silver chloride crystals [C] . Anatoly N. Latyshev, Oleg V.Ovchinnikov, ictor G. Klyuev, International congress of imaging science . 2002

机译：吸附在氯化银晶体上的银的电离和解吸能
5. The Transition of Adsorbed Water Vapour on Silica to Adsorbed Water [D] . Saber, Sepehr. 2018

机译：吸附水蒸气在二氧化硅中的过渡到吸附水
6. Photophysical Studies of a New Water Soluble Indocarbocyanine Dye Adsorbed onto Microcrystalline Cellulose and β-Cyclodextrin [O] . Reda M. El-Shishtawy, Anabela S. Oliveira, Paulo Almeida, 2013

机译：一种新型水溶性吲哚并花菁染料吸附在微晶纤维素和β-环糊精上的光物理研究
7. Electric-field-dependent empirical potentials for molecules and crystals: a first application to flexible water molecule adsorbed in zeolites [O] . Cicu, P., Demontis, Pierfranco, Spanu, Silvano, 2000

机译：分子和晶体的电场相关经验势：分子筛中吸附的柔性水分子的首次应用
8. Surface Crystallography of Clean Platinum Single Crystals and Adsorbed Hydrocarbon Overlayers Studied by Low Energy Electron Diffraction [R] . Stair, P. C. 1977

机译：低能电子衍射研究清洁铂单晶和吸附烃层的表面晶体学

States of water adsorbed on perindopril crystals

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