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首页> 外文期刊>Onkologie >Acute tumor lysis syndrome after transarterial chemoembolization for well-differentiated hepatocellular carcinoma with neuroendocrine features.
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Acute tumor lysis syndrome after transarterial chemoembolization for well-differentiated hepatocellular carcinoma with neuroendocrine features.

机译:经动脉化疗栓塞后的急性肿瘤溶解综合征,用于具有神经内分泌功能的高分化肝细胞癌。

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BACKGROUND: Acute tumor lysis syndrome (ATLS) was gradually considered as a separate entity or condition associated with bulk tumor treatment. There are few reports of ATLS following transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC). Primary HCCs with neuroendocrine features are also extremely rare. CASE REPORT: We report such a rare case of well-differentiated (WD)-HCC with neuroendocrine features, which presented with ATLS after TACE. The patient was a 54-year-old female. Needle biopsy of the liver histologically confirmed WD-HCC. On the 5th postoperative day, the patient was identified as having ATLS. Hemodialysis was done while her renal functions recovered. In the follow-up visits, computed tomography results showed distinct reduction in tumor size. CONCLUSIONS: When a large HCC with rich blood supply undergoes TACE, we should pay attention to the possibility of ATLS. Close monitoring after antineoplastic therapy in high-risk patients is warranted.
机译:背景:急性肿瘤溶解综合征(ATLS)逐渐被认为是与大块肿瘤治疗相关的单独实体或病症。肝细胞癌(HCC)患者经动脉化疗栓塞(TACE)后发生ATLS的报道很少。具有神经内分泌功能的原发性肝癌也极为罕见。病例报告:我们报告了这种罕见的具有神经内分泌功能的高分化(WD)-HCC病例,在TACE后出现ATLS。该患者是一名54岁的女性。肝脏的穿刺活检在组织学上证实为WD-HCC。术后第5天,该患者被确认患有ATLS。在她的肾功能恢复的同时进行了血液透析。在随访中,计算机断层扫描结果显示肿瘤大小明显减少。结论:当大量肝癌且血液供应丰富时,进行TACE时,应注意ATLS的可能性。在高危患者中,抗肿瘤治疗后应严密监视。

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