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Coinfection of pneumocystis jirovecii and invasive pulmonary aspergillosis in an immunocompromised patient: A diagnostic challenge

机译:免疫力低下患者肺炎支原体肺孢子虫和侵袭性肺曲霉病的合并感染:诊断挑战

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Background: Invasive infections caused by Aspergillus fumigatus as well as Pneumocystis pneumonia are serious and often lethal diseases in severely immunocompromised patients. Case Report: We report on a rare case of a pulmonary coinfection of Pneumocystis jirovecii and Aspergillus fumigatus in a 59-year-old female patient with a history of astrocytoma treated with high doses of corticosteroids and a subsequent CD4 lymphocyte count of 30/μl. Conclusion: A heightened clinical awareness and a stringent and accurate diagnostic work-up encompassing diagnostic tools to detect even coincident fungal infections is crucial for sufficient and early antifungal treatment in immunocompromised patients with lung infiltrates.
机译:背景:由烟曲霉和肺孢子虫肺炎引起的侵袭性感染是严重的,通常是严重免疫功能低下的患者致死性疾病。病例报告:我们报告了一位罕见的病例,该病例为一例59岁女性患者的肺部合并肺吸虫jirovecii和烟曲霉,曾有高剂量皮质类固醇治疗星形细胞瘤史,随后CD4淋巴细胞计数为30 /μl。结论:增强临床认识和严格而准确的诊断工作,包括能够检测甚至同时发生的真菌感染的诊断工具,对于免疫受损的肺浸润患者进行充分,早期的抗真菌治疗至关重要。

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