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Diagnosis and treatment of a patient with isolated spinal granulocytic sarcoma: A case report

机译：一例孤立性脊髓粒细胞肉瘤的诊治：一例报告

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A previously healthy 34-year-old female presented with a 5-month history of progressive backache and weakness in the left fingers. Magnetic resonance imaging (MRI) showed soft tissue masses in the spinal canal distributed along the nerve course. The patient's baseline laboratory data were normal. Surgical intervention was performed and histological examination identified isolated spinal granulocytic sarcoma (GS). A bone marrow biopsy also presented normal findings. However, the patient developed numbness and pain in the right lower limb two months later. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) showed FDG uptake in the left trapezius muscle, cervix uteri, iliac bone, lymphadenectasis of the pelvic wall and left axillary fossa. Cerebrospinal fluid (CSF) examination allowed a diagnosis of central nervous system leukemia (CNSL). The patient underwent chemotherapy and intrathecal injection, resulting in the elimination of the residual lesion. Correct diagnosis and adequate treatment are essential to achieve optimal results in patients with isolated spinal GS.
机译：先前健康的34岁女性表现出5个月的进行性背痛和左手指无力的病史。磁共振成像（MRI）显示沿神经进程分布的椎管内软组织肿块。患者的基线实验室数据正常。进行了手术干预，并进行了组织学检查，发现了孤立的脊髓颗粒肉瘤（GS）。骨髓活检也显示正常结果。但是，两个月后，患者右下肢出现了麻木和疼痛。氟代葡萄糖（FDG）-正电子发射断层扫描（PET）显示FDG在左斜方肌，子宫颈，骨，骨盆壁淋巴结肿大和左腋窝被摄取。脑脊液（CSF）检查可以诊断为中枢神经系统白血病（CNSL）。该患者接受了化学疗法和鞘内注射，从而消除了残留病变。正确的诊断和适当的治疗对于孤立性脊柱GS患者取得最佳疗效至关重要。

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