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首页> 外文期刊>Oncology letters >Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns
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Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns

机译：放射肿瘤学中的正常组织研究：对被高引用的文章和引用模式的系统评价

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摘要

Radiation therapy is one of the cornerstones of modern multidisciplinary cancer treatment. Normal tissue tolerance is critical as radiation-induced side effects may compromise organ function and quality of life. The importance of normal tissue research is reflected by the large number of scientific articles, which have been published between 2006 and 2010. The present study identified important areas of research as well as seminal publications. The article citation rate is among the potential indicators of scientific impact. Highly cited articles, arbitrarily defined as those with ≥15 citations, were identified via a systematic search of the citation database, Scopus. Up to 608 articles per year were published between 2006 and 2010, however, <10% of publications in each year accumulated ≥15 citations. This figure is notably low, when compared with other oncology studies. A large variety of preclinical and clinical topics, including toxicity prediction, the dose-volume relationship and radioprotectors, accumulated ≥15 citations. However, clinical prevention or mitigation studies were underrepresented. The following conclusion may be drawn from the present study; despite the improved technology that has resulted in superior dose distribution, clinical prevention or mitigation studies are critical and must receive higher priority, funding and attention.
机译：放射治疗是现代多学科癌症治疗的基石之一。正常组织的耐受性至关重要，因为辐射引起的副作用可能会损害器官功能和生活质量。正常组织研究的重要性反映在2006年至2010年之间发表的大量科学文章中。本研究确定了重要的研究领域和开创性出版物。文章引用率是科学影响力的潜在指标之一。通过对引文数据库Scopus进行系统搜索，可以找到被高引用的文章，这些文章被任意定义为被引用次数≥15的文章。在2006年至2010年期间，每年最多发表608篇文章，但是，每年少于<10％的出版物被引用次数≥15。与其他肿瘤学研究相比，该数字明显偏低。大量的临床前和临床主题，包括毒性预测，剂量-体积关系和辐射防护剂，被引用次数≥15。但是，临床预防或缓解研究的代表性不足。从本研究中可以得出以下结论;尽管经过改进的技术已导致了更好的剂量分配，但临床预防或缓解研究仍然至关重要，必须得到更高的优先级，资金和关注。

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