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首页> 外文期刊>Oncology letters >Outcomes for patients who are diagnosed with breast and endometrial cancer
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Outcomes for patients who are diagnosed with breast and endometrial cancer

机译：诊断为乳腺癌和子宫内膜癌的患者的结局

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摘要

The present study sought to determine the survival outcomes for women diagnosed with breast and endometrial cancer. Using SEER data, a population-based cohort study of women diagnosed with breast and endometrial cancer was conducted. Kaplan-Meier survival curves were created for disease-specific survival rates. A total of 2,027 women diagnosed with breast and endometrial cancer were identified. Of these, 1,296 (63.9%) developed breast cancer first and 731 (36.1%) developed endometrial cancer first. Regional lymph node involvement was significantly more common with a breast cancer diagnosis [522 (25.8%) women] compared with an endometrial cancer diagnosis [87 (4.3%) women] (P<0.05). Factors associated with decreased survival included a high tumor grade in endometrial cancer, nodal positivity and estrogen receptor-negative breast cancer (P<0.05 for each). There were 83 (4.1%) mortalities due to breast cancer, 63 (3.1%) mortalities due to endometrial cancer and 178 (8.8%) mortalities due to other causes (P<0.05). In conclusion, for women diagnosed with breast and endometrial cancer, the cumulative risk of mortality at five years following the second cancer diagnosis is nearly four times more likely to be due to breast cancer than endometrial cancer.
机译：本研究试图确定被诊断患有乳腺癌和子宫内膜癌的妇女的生存结果。使用SEER数据，对诊断出患有乳腺癌和子宫内膜癌的女性进行了基于人群的队列研究。 Kaplan-Meier生存曲线是针对特定疾病的生存率创建的。总共确定了2027名被诊断患有乳腺癌和子宫内膜癌的妇女。其中，有1,296名（63.9％）首先患乳腺癌，而有731名（36.1％）首先患子宫内膜癌。乳腺癌诊断[522（25.8％）妇女]比子宫内膜癌诊断[87（4.3％）妇女]显着更常见于区域淋巴结受累（P <0.05）。与存活率降低相关的因素包括子宫内膜癌的肿瘤高分级，淋巴结阳性和雌激素受体阴性的乳腺癌（每项P <0.05）。乳腺癌导致的死亡率为83（4.1％），子宫内膜癌的死亡率为63（3.1％），其他原因的死亡率为178（8.8％）（P <0.05）。总之，对于被诊断患有乳腺癌和子宫内膜癌的妇女，第二次癌症诊断后五年内的累积死亡风险是子宫内膜癌的几倍。

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