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首页> 外文期刊>Oncology letters >Therapy for thoracic lumbar and sacral vertebrae tumors using total spondylectomy and spine reconstruction through posterior or combined anterior-posterior approaches
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Therapy for thoracic lumbar and sacral vertebrae tumors using total spondylectomy and spine reconstruction through posterior or combined anterior-posterior approaches

机译：通过全脊椎切除术和后路或前后路联合后路重建脊柱治疗胸腰椎和骨椎骨肿瘤

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摘要

The present study aimed to analyze the indications, feasibility, safety and clinical effects of total spondylectomy and spine reconstruction through posterior or combined anterior-posterior approaches for thoracic lumbar and sacral vertebrae tumors. Between December 2009 and May 2012, 10 patients with thoracic lumbar and sacral vertebrae tumors were retrospectively analyzed. Different surgical indications and approaches were used according to the affected segments, the extent of lesion involvement and the specific pathology results. One-stage posterior or combined anterior-posterior total spondylectomy and reconstruction was used for the treatment of complicated thoracic lumbar and sacral vertebral malignant tumors and invasive benign tumors. The duration of surgery, levels of intraoperative blood loss and transfusions, and the clinical effects were observed. The average surgical duration was 6.8 h (range, 4.8-12 h), with an average blood loss level of 3,200 ml (range, 1,500-10,000 ml) and an average transfusion level of 2,500 ml. During the average 15 months (range, 3-29 months) follow up, two patients succumbed and one patient experienced tumor recurrence. Neither tumor reoccurrence nor metastasis was observed in all other patients. Personalized surgical indications and approaches according to the affected segments, the extent of lesion involvement and the specific pathology results would aid in the reduction of pain, the improvement of nerve function and the reduction of tumor recurrence.
机译：本研究旨在通过胸腰椎和椎椎体肿瘤的后路或前后路联合方法分析全脊椎切除术和脊柱重建的适应症，可行性，安全性和临床效果。在2009年12月至2012年5月之间，对10例胸腰and骨椎骨肿瘤患者进行了回顾性分析。根据受影响的部位，病变累及的程度和特定的病理结果，使用了不同的手术适应症和方法。一期后路或前后路联合全脊椎切除术和重建术用于治疗复杂的胸腰椎和椎椎体恶性肿瘤和浸润性良性肿瘤。观察手术时间，术中失血和输血水平以及临床效果。平均手术时间为6.8小时（范围4.8-12小时），平均失血量为3200毫升（范围为1500-10,000毫升），平均输血量为2500毫升。在平均15个月（范围3-29个月）的随访中，两名患者屈服，一名患者出现肿瘤复发。在所有其他患者中均未观察到肿瘤复发或转移。根据受影响的部位，病变累及的程度和特定的病理结果进行个性化的手术适应症和方法将有助于减轻疼痛，改善神经功能和减少肿瘤复发。

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