...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Ophthalmic plastic and reconstructive surgery >Surgical management of locally advanced adenoid cystic carcinoma of the lacrimal gland.
【24h】

Surgical management of locally advanced adenoid cystic carcinoma of the lacrimal gland.

机译：泪腺局部晚期腺样囊性癌的外科治疗。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To review our experience with multidisciplinary surgical management of locally advanced adenoid cystic carcinoma of the lacrimal gland. METHODS: We present a case series of 7 patients with lacrimal gland adenoid cystic carcinoma treated at our institution between June 2001 and October 2003. Clinical records, histologic sections, and radiographic images were reviewed. RESULTS: The study included 3 men and 4 women (mean age at diagnosis, 44 years). All 7 patients underwent an orbital exenteration with bone removal. Five patients had an orbitectomy through a craniotomy approach and 2 patients had an exenteration through a fronto-orbito-zygomatic approach, all with removal of the bone of the superior and lateral wall. Six patients underwent reconstruction of the socket through the use of a vascularized flap. The surgical approach involved a neurosurgeon, an oculoplastic or head and neck surgeon, and a plastic surgeon. Six patients received postoperative radiation therapy. One patient with a recurrent tumor had already received radiation therapy, which precluded additional radiation therapy after surgical resection. The radiation field included the orbit and the skull base because all patients had evidence of perineural invasion. As of this writing, there have been no local recurrences. Five patients had development of distant metastases and died of disease, at follow-up times from 12 to 32 months after surgery. Two patients are alive without evidence of disease, both at 24 months' follow-up. CONCLUSIONS: Orbitectomy with bone removal may be indicated for achieving local and regional control in advanced cases of adenoid cystic carcinoma of the lacrimal gland. This surgery does not decrease the risk of distant metastasis. The cases in our series highlight the locally invasive and metastatic behavior of this cancer.
机译：目的：回顾我们在泪腺局部晚期腺样囊性癌多学科外科治疗中的经验。方法：我们介绍了2001年6月至2003年10月间在我院接受治疗的7例泪腺腺样囊性囊性癌患者的病例系列。结果：该研究包括3名男性和4名女性（诊断时的平均年龄为44岁）。所有7例患者均接受了眶内拔除术。 5例患者通过颅骨切开术进行了眼眶切除术，2例患者通过额眶眶-go骨入路术消了肠炎，所有患者均切除了上，外侧骨。六名患者通过使用血管化皮瓣进行了承窝重建。手术方法包括神经外科医生，眼部整形或头颈外科医生和整形外科医生。六例患者接受了术后放射治疗。一名患有复发性肿瘤的患者已接受放射治疗，因此在手术切除后无法进行其他放射治疗。辐射场包括眼眶和颅底，因为所有患者都有神经周浸润的证据。在撰写本文时，还没有局部复发。术后12到32个月的随访时间中，有5名患者发生远处转移并死于疾病。两名患者均在24个月的随访中存活，没有疾病迹象。结论：在晚期泪腺腺样囊性癌病例中，行骨切除术可达到局部和区域控制的目的。该手术不会降低远处转移的风险。我们系列中的病例强调了这种癌症的局部侵袭和转移行为。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号