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首页> 外文期刊>Optometry and vision science: official publication of the American Academy of Optometry >Longitudinal quantitative assessment of vision function in children with cortical visual impairment.
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Longitudinal quantitative assessment of vision function in children with cortical visual impairment.

机译:皮层视力障碍儿童视觉功能的纵向定量评估。

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摘要

PURPOSE: Cortical visual impairment (CVI) is bilateral visual impairment caused by damage to the posterior visual pathway, the visual cortex, or both. Current literature reports great variability in the prognosis of CVI. The purpose of this study was to evaluate change in vision function in children with CVI over time using a quantitative assessment method. METHODS: The visual acuity and contrast sensitivity of children with CVI were retrospectively assessed using the sweep visual evoked potential (VEP). Thirty-nine children participated in the visual acuity assessment and 34 of the 39 children participated in the contrast threshold assessment. At the time of the first VEP, the children ranged in age from 1 to 16 years (mean: 5.0 years). The time between measures ranged from 0.6 to 13.7 years (mean: 6.5 years). RESULTS: Forty-nine percent of the children studied showed significant improvement of visual acuity. The average improvement was 0.43 log unit (mean change: 20/205 to 20/76) in those who improved. The initial visual acuity was worse in those who improved compared with those who did not improve (p < 0.001). Forty-seven percent of the children studied showed significant improvement of contrast threshold. In those who improved, the average amount of improvement was 0.57 log unit (10 to 2.6% Michelson). The initial contrast threshold was significantly worse in those who improved compared with those who did not improve (p = 0.001). Also, the change in contrast threshold was related to age of the child (p = 0.017). CONCLUSIONS: Significant improvement in vision function can occur over time in children with CVI. In the present study, approximately 50% of the children improved and the remainder remained stable. No relation was found between etiology and improvement. Further investigation is warranted to better understand the prognosis for visual recovery in children with CVI.
机译:目的:皮质视力障碍(CVI)是由对后视路,视皮质或两者的损害引起的双侧视力障碍。当前文献报道了CVI的预后有很大的变化。这项研究的目的是使用定量评估方法评估CVI儿童视力功能随时间的变化。方法:使用扫描视觉诱发电位(VEP)回顾性评估CVI儿童的视敏度和对比敏感性。 39名儿童参加了视力评估,39名儿童中有34名参加了对比阈值评估。在首次接受VEP时,孩子的年龄为1至16岁(平均:5.0岁)。两次测量之间的时间间隔为0.6到13.7年(平均:6.5年)。结果:49%的儿童表现出明显的视力改善。改善者的平均改善为0.43 log单位(平均变化:20/205至20/76)。与没有改善的患者相比,有改善的患者的初始视力较差(p <0.001)。研究的儿童中有47%的人显示对比度阈值有显着改善。在那些有改善的人中,平均改善量为0.57 log单位(迈克尔逊10到2.6%)。与没有改善的患者相比,有改善的患者的初始对比度阈值明显更差(p = 0.001)。同样,对比度阈值的变化与孩子的年龄有关(p = 0.017)。结论:随着时间的流逝,CVI患儿的视力功能可显着改善。在本研究中,大约50%的儿童有所改善,其余的保持稳定。在病因和改善之间未发现任何关系。有必要进行进一步的调查,以更好地了解CVI儿童视力恢复的预后。

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