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首页> 外文期刊>Ophthalmic surgery, lasers & imaging: the official journal of the International Society for Imaging in the Eye >Analysis of the relationship between drusen size and drusen area in eyes with age-related macular degeneration.
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Analysis of the relationship between drusen size and drusen area in eyes with age-related macular degeneration.

机译：年龄相关性黄斑变性的眼玻璃膜疣大小与玻璃膜疣面积的关系分析。

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摘要

BACKGROUND AND OBJECTIVE: To examine the relationship between drusen counts and drusen area in eyes with age-related macular degeneration, and to correlate drusen areas between fellow eyes. PATIENTS AND METHODS: Digital images from 378 patients (756 eyes) were analyzed using a validated drusen detection algorithm. Total drusen area and the number of drusen of various sizes (small: < 62 microns, intermediate: 63-124 microns, large: 125-249 microns, etc) were recorded for the central 1,000- and 3,000-micron diameter macular regions. Correlations were assessed using structural equation models. RESULTS: For the 1,000-micron region, the number of intermediate drusen was more highly correlated to total drusen area than the number of large drusen (R = 0.91 vs 0.82); this difference was statistically significant. The correlation coefficients for drusen area between fellow eyes was 0.73. CONCLUSION: The number of large drusen does not correlate better with total drusen area than drusen of other sizes. The number of large drusen is not necessarily a good surrogate for total drusen area.
机译：背景与目的：探讨与年龄相关的黄斑变性的眼睛的玻璃膜疣数与玻璃膜疣区域的关系，并关联另一只眼睛的玻璃膜疣区域。患者和方法：使用经过验证的玻璃疣检测算法分析了378例患者（756眼）的数字图像。记录了中心黄斑区域直径1,000至3,000微米的各种玻璃疣的总玻璃疣面积和大小（小：<62微米，中间：63-124微米，大：125-249微米等）。使用结构方程模型评估相关性。结果：在1000微米区域，中间玻璃疣的数量与玻璃疣总面积的相关性大于大玻璃疣的数量（R = 0.91 vs 0.82）;这种差异具有统计学意义。两只眼睛之间的玻璃疣面积的相关系数为0.73。结论：大玻璃疣的数量与其他玻璃疣的相关性并不更好。大玻璃瓶的数量并不一定是整个玻璃瓶面积的良好替代。

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