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首页> 外文期刊>Ophthalmology >Spontaneous corneal clearing after Descemet's stripping without endothelial replacement
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Spontaneous corneal clearing after Descemet's stripping without endothelial replacement

机译：Descemet剥离后自发角膜清除，不更换内皮

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摘要

Purpose: To report spontaneous corneal clearing with improved visual acuity and central endothelial cell repopulation after Descemet's stripping without endothelial replacement. Design: Interventional case report. Methods: A 34-year-old woman with bilateral decreased vision secondary to corneal edema from endothelial dysfunction underwent Descemet's stripping endothelial keratoplasty (DSEK) in the right eye and Descemet's stripping only in the left eye. Histopathologic evaluation confirmed a dual diagnosis of Fuchs' endothelial dystrophy and posterior polymorphous membrane dystrophy from Descemet's membrane specimens removed from each eye. After primary graft failure with regraft in the right eye, the second posterior corneal lenticule detached and was removed and not replaced. The cornea cleared, and central endothelial cell repopulation was documented by confocal microscopy. Therefore, Descemet's stripping without endothelial replacement was performed in the left eye. The left cornea also cleared with central endothelial cell repopulation. Main Outcome Measures: Postoperative visual acuity and central endothelial cell repopulation. Results: Endothelial migration after Descemet's stripping alone in the left eye, with probable host endothelial cell repopulation in the right eye. Conclusions: Endothelial cell migration after Descemet's stripping procedure without insertion of endothelial graft can occur, resulting from host endothelial cell repopulation with corneal clearing and improved visual acuity. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
机译：目的：报告在Descemet剥离后无需内皮替代的情况下，自发角膜清除术具有改善的视敏度和中央内皮细胞的聚集。设计：介入病例报告。方法：一名34岁女性因内皮功能障碍继发角膜水肿导致双侧视力下降，右眼接受Descemet剥离内皮角膜移植术（DSEK），仅左眼接受Descemet剥离。组织病理学评估证实了双重诊断，即从每只眼睛摘下的Descemet膜标本中可以得出Fuchs内皮营养不良和后部多形性膜营养不良。在右眼初次移植失败并再次移植后，第二个角膜后巩膜脱离并被移除，没有被更换。角膜已清除，共聚焦显微镜记录了中央内皮细胞的重新聚集。因此，在左眼进行了不使用内皮替代物的Descemet剥离。中央角膜内皮细胞重新聚集也清除了左角膜。主要观察指标：术后视力和中央内皮细胞的重新聚集。结果：左眼仅在Descemet剥离后，内皮细胞迁移，右眼中可能存在宿主内皮细胞重新聚集。结论：Descemet剥离手术后未插入内皮移植物，可能发生内皮细胞迁移，这是由于宿主内皮细胞重新充满角膜并提高了视力而导致的。财务披露：作者对本文讨论的任何材料均没有所有权或商业利益。

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