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首页> 外文期刊>Ophthalmology >The Los Angeles Latino Eye Study: design, methods, and baseline data.
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The Los Angeles Latino Eye Study: design, methods, and baseline data.

机译：洛杉矶拉丁裔眼研究：设计，方法和基线数据。

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摘要

OBJECTIVE: To describe the study design, operational strategies, procedures, and baseline characteristics of the Los Angeles Latino Eye Study (LALES), a population-based assessment of the prevalence of visual impairment, ocular disease, and visual functioning in Latinos. DESIGN: Population-based, cross-sectional study. PARTICIPANTS: Six thousand three hundred fifty-seven Latinos 40 years and older from 6 census tracts in Los Angeles, California. METHODS: A detailed interview and eye examination were performed on each eligible participant. The interview included an assessment of demographic, behavioral, and ocular risk factors and health-related and vision-related quality of life. The eye examination included a measurement of visual acuity, intraocular pressure, and visual fields; fundus and optic disc photography; a detailed anterior and posterior segment examination; and measurement of blood pressure, glycosylated hemoglobin levels, and blood glucose levels. MAIN OUTCOME MEASURES: Prevalence of visualimpairment, blindness, cataract, glaucoma, diabetic retinopathy, and age-related macular degeneration constitute the study's primary outcome variables. Secondary outcomes include odds ratios for risk factors associated with eye disease, health-related quality of life, and vision-related quality of life. Response rates and baseline characteristics are presented. RESULTS: Of the 7789 individuals eligible for LALES, 6357 (82%) had a clinical examination; an additional 524 completed only an in-home interview. The majority of participants were female (58%), the average (+/- standard deviation) age was 54.9 (+/-10.8) years, and 80.0% were of Mexican origin and 0.4% self-identified as American Indian or Alaskan Native. The age distribution of LALES participants was similar to that of Latinos of Mexican origin in the rest of the United States. CONCLUSION: The LALES has recruited Latinos 40 and older for an ophthalmic epidemiologic study. The LALES cohort will provide information about the prevalence and risk factors of ocular disease in the largest and fastest growing minority in the United States.
机译：目的：描述洛杉矶拉丁裔眼睛研究（LALES）的研究设计，操作策略，程序和基线特征，这是一项基于人群的拉丁裔视力障碍，眼病和视觉功能患病率评估。设计：基于人群的横断面研究。参加者：来自加利福尼亚州洛杉矶的6个人口普查区中的40岁及63岁以上的拉丁美洲人637名。方法：对每位合格的参与者进行详细的访谈和眼睛检查。访谈包括对人口，行为和眼部危险因素以及与健康有关和与视觉有关的生活质量的评估。眼睛检查包括视力，眼压和视野的测量。眼底和光盘摄影;详细的前后节检查;并测量血压，糖基化血红蛋白水平和血糖水平。主要观察指标：视力障碍，失明，白内障，青光眼，糖尿病性视网膜病变和年龄相关性黄斑变性的患病率是本研究的主要结果变量。次要结果包括与眼部疾病，健康相关的生活质量以及视力相关的生活质量相关的危险因素的比值比。给出了响应率和基线特征。结果：在7789名符合LALES资格的人中，有6357名（82％）接受了临床检查;另外524个仅完成了一次家庭访问。大部分参与者为女性（58％），平均年龄（+/-标准差）为54.9（+/- 10.8）岁，其中80.0％为墨西哥裔，0.4％为美国印第安人或阿拉斯加原住民。 LALES参与者的年龄分布与美国其他地区的墨西哥裔拉丁美洲人相似。结论：LALES招募了40岁及以上的拉丁裔进行眼科流行病学研究。 LALES队列将提供有关美国最大，增长最快的少数民族中眼病患病率和危险因素的信息。

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