...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Ophthalmology >Major eye diseases and risk factors associated with systemic hypertension in an adult Chinese population: the Beijing Eye Study.
【24h】

Major eye diseases and risk factors associated with systemic hypertension in an adult Chinese population: the Beijing Eye Study.

机译：中国成年人眼中与系统性高血压相关的主要眼部疾病和危险因素：北京眼科研究。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To assess the relationship of hypertension with major eye diseases and other ocular parameters. DESIGN: Population-based study. PARTICIPANTS: The Beijing Eye Study is a population-based study that included 4439 Chinese subjects examined at the baseline examination in 2001; there was a follow-up examination in 2006, in which 3251 subjects participated, of whom 3222 had blood pressure measurements. METHODS: All participants underwent an ophthalmic examination, anthropometric measurements, and blood pressure measurement. Hypertension was defined as a systolic blood pressure >or=140 mmHg and/or diastolic blood pressure >or=90 mmHg, and/or self-reported current treatment for hypertension with antihypertensive medication. MAIN OUTCOME MEASURES: Blood pressure and ocular parameters, including intraocular pressure and prevalence of major ophthalmic diseases. RESULTS: Mean age of participants in the present study was 60.4+/-10.0 years. Hypertension was present in 1500 (46.6%) of the 3222 subjects who had their blood pressure measured. In multiple regression analysis, hypertension was associated with higher intraocular pressure (beta = 0.39; 95% confidence interval [CI], 0.12-0.66; P = 0.005), focal arteriolar narrowing (odds ratio [OR], 1.78; 95% CI, 1.34-2.36; P<0.001), arteriovenous nicking (OR, 1.50; 95% CI, 1.11-2.04; P = 0.009), generalized retinal arteriolar narrowing (OR, 1.65; 95% CI, 1.30-2.09; P<0.001), retinal vein occlusions (OR, 2.86; 95% CI, 1.21-6.80; P = 0.02), and diabetic retinopathy (OR, 1.90; 95% CI, 1.08-3.31; P = 0.02). Hypertension was not significantly associated with the prevalence of open-angle glaucoma (P = 0.19), angle-closure glaucoma (P = 0.15), age-related macular degeneration (AMD) (P = 0.73), nuclear cataract (P = 0.88), posterior subcapsular cataract (P = 0.30), cortical cataract (P = 0.10), or area of alpha zone (P = 0.05) or beta zone of parapapillary atrophy (P = 0.95). CONCLUSIONS: In Chinese persons, while controlling for other systemic parameters, hypertension was associated with increased intraocular pressure, retinal microvascular abnormalities, and prevalence of retinal vein occlusion and diabetic retinopathy. Hypertension was not associated significantly with AMD, age-related cataract, or glaucoma.
机译：目的：评估高血压与主要眼病和其他眼参数的关系。设计：基于人群的研究。参加者：北京眼研究是一项基于人群的研究，其中包括4439名在2001年进行基线检查的中国受试者。 2006年进行了一项随访检查，有3251名受试者参加，其中3222名受试者进行了血压测量。方法：所有参与者均接受眼科检查，人体测量和血压测量。高血压定义为收缩压>或= 140 mmHg和/或舒张压>或= 90 mmHg，和/或使用抗高血压药物自我报告的当前高血压治疗方法。主要观察指标：血压和眼参数，包括眼内压和主要眼科疾病的患病率。结果：本研究参与者的平均年龄为60.4 +/- 10.0岁。在测量血压的3222名受试者中，有1500名（46.6％）患有高血压。在多元回归分析中，高血压与较高的眼内压（β= 0.39; 95％置信区间[CI]，0.12-0.66; P = 0.005），局灶性小动脉狭窄（比值比[OR]，1.78; 95％CI， 1.34-2.36; P <0.001），动静脉切迹（OR，1.50; 95％CI，1.11-2.04; P = 0.009），广义视网膜小动脉狭窄（OR，1.65; 95％CI，1.30-2.09; P <0.001） ，视网膜静脉阻塞（OR，2.86; 95％CI，1.21-6.80; P = 0.02）和糖尿病性视网膜病变（OR，1.90; 95％CI，1.08-3.31; P = 0.02）。高血压与开角型青光眼（P = 0.19），闭角型青光眼（P = 0.15），年龄相关性黄斑变性（AMD）（P = 0.73），核性白内障（P = 0.88）的发生率无显着相关性，后囊状白内障（P = 0.30），皮质性白内障（P = 0.10）或乳头旁萎缩的α区（P = 0.05）或β区（P = 0.95）。结论：在中国人中，在控制其他系统参数的同时，高血压与眼内压升高，视网膜微血管异常以及视网膜静脉阻塞和糖尿病性视网膜病变的患病率有关。高血压与AMD，年龄相关性白内障或青光眼没有显着相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号