Submicrometer axial resolution optical coherence tomography

B. Povazay; K. Bizheva; A. Unterhuber; B. Hermann; H. Sattmann; A. F. Fercher; W. Drexler; A. Apolonski; W. J. Wadsworth; J. C. Knight; P. St. J. Russell; M. Vetterlein; E. Scherzer

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Submicrometer axial resolution optical coherence tomography

机译：亚微米轴向分辨率光学相干断层扫描

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Optical coherence tomography (OCT) with unprecedented submicrometer axial resolution achieved by use of a photonic crystal fiber in combination with a compact sub-10-fs Ti:sapphire laser (Femtolasers Produktions) is demonstrated for what the authors believe is the first time. The emission spectrum ranges from 550 to 950 nm (λ_(c)=725 nm, P_(out)=27 mW), resulting in a free-space axial OCT resolution of ～0.75 μm, corresponding to ～0.5 μm in biological tissue. Submicrometer-resolution OCT is demonstrated in vitro on human colorectal adenocarcinoma cells HT-29. This novel light source has great potential for development of spectroscopic OCT because its spectrum covers the absorption bands of several biological chromophores.

机译：通过将光子晶体光纤与紧凑的sub-10-fs Ti：蓝宝石激光器（Femtolasers Produktions）结合使用，可以实现具有前所未有的亚微米轴向分辨率的光学相干断层扫描（OCT），这是作者首次相信。发射光谱范围为550至950 nm（λ_（c）= 725 nm，P_（out）= 27 mW），导致自由空间轴向OCT分辨率约为0.75μm，相当于生物组织中的〜0.5μm。在人大肠腺癌细胞HT-29上体外证明了亚微米级分辨率的OCT。这种新型光源具有开发光谱OCT的巨大潜力，因为它的光谱覆盖了几种生物发色团的吸收带。

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《Optics Letters》 |2002年第20期|共3页
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B. Povazay; K. Bizheva; A. Unterhuber; B. Hermann; H. Sattmann; A. F. Fercher; W. Drexler; A. Apolonski; W. J. Wadsworth; J. C. Knight; P. St. J. Russell; M. Vetterlein; E. Scherzer;
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1. Submicrometer axial resolution optical coherence tomography [J] . B. Povazay, K. Bizheva, A. Unterhuber, Optics Letters . 2002,第20期

机译：亚微米轴向分辨率光学相干断层扫描
2. Long scan depth optical coherence tomography on imaging accommodation:impact of enhanced axial resolution,signal-to-noise ratio and speed [J] . Yilei Shao, Aizhu Tao, Hong Jiang, 眼视光学杂志（英文版） . 2019,第003期

机译：长扫描深度光学相干层析成像对成像适应性的影响：增强的轴向分辨率，信噪比和速度的影响
3. Optical coherence tomography (OCT) with 2?nm axial resolution using a compact laser plasma soft X-ray source [J] . Przemys?aw Wachulak, Andrzej Bartnik, Henryk Fiedorowicz Scientific reports. . 2018,第1期

机译：使用紧凑型激光等离子体软X射线源的2 nm nm轴向分辨率的光学相干断层扫描（OCT）
4. Axial resolution and depth range of high-resolution spectral domain optical coherence tomography at 1.3 μm [C] . Sang-Won Lee, Hyun-Woo Jeong, Yeh-Chan Ahn, Conference on optical coherence tomography and coherence domain optical methods in biomedicine XIII; 20090126-28; San Jose, CA(US) . 2009

机译：高分辨率光谱域光学相干断层扫描的轴向分辨率和深度范围为1.3μm
5. Axial and Lateral Resolution in Optical Coherence Tomography as a Function of System and Tissue Optical Properties [D] . Sipos, Ryan 2019

机译：光学相干断层扫描的轴向和横向分辨率与系统和组织光学特性的关系
6. Long scan depth optical coherence tomography on imaging accommodation: impact of enhanced axial resolution signal-to-noise ratio and speed [O] . Yilei Shao, Aizhu Tao, Hong Jiang, 2018

机译：长扫描深度光学相干层析成像对成像适应性的影响：增强的轴向分辨率信噪比和速度的影响
7. Axial resolution and signal-to-noise ratio in deep-tissue imaging with 1.7 - μ m high-resolution optical coherence tomography with an ultrabroadband laser source [O] . Hiroyuki Kawagoe, Masahito Yamanaka, Norihiko Nishizawa 2017

机译：深层组织成像中的轴向分辨率和信噪比用1.7 - μM高分辨率光学相干断层扫描，具有超载带电源

Submicrometer axial resolution optical coherence tomography

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