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首页> 外文期刊>Optics Letters >Functional optical coherence tomography for detecting neural activity through scattering changes
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Functional optical coherence tomography for detecting neural activity through scattering changes

机译：通过散射变化检测神经活动的功能性光学相干断层扫描

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We have demonstrated functional optical coherence tomography (fOCT) for neural imaging by detecting scattering changes during the propagation of action potentials through neural tissue. OCT images of nerve fibers from the abdominal ganglion of the sea slug Aplysia calafornica were taken before, during, and after electrical stimulation. Images acquired during stimulation showed localized reversible increases in scattering compared with those acquired before stimulation. Motion-mode OCT images of nerve fibers showed transient scattering changes from spontaneous action potentials. These results demonstrate that OCT is sensitive to the optical changes in electrically active nerve fibers. (C) 2003 Optical Society of America. [References: 7]
机译：我们已经通过检测动作电位通过神经组织传播过程中的散射变化，展示了用于神经成像的功能性光学相干断层扫描（fOCT）。在电刺激之前，期间和之后拍摄海Aplysia calafornica腹部神经节的神经纤维的OCT图像。与刺激之前获得的图像相比，刺激期间获得的图像显示散射的局部可逆增加。神经纤维的运动模式OCT图像显示自发动作电位产生的瞬时散射变化。这些结果表明，OCT对电活动神经纤维的光学变化敏感。 （C）2003年美国眼镜学会。 [参考：7]

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