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Optofluidic particle concentration by a long-range dual-beam trap

机译:远距离双光束阱对光流体颗粒的浓缩

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Ultrahigh sensitivity detection of particles in solution implies the ability to detect at very low concentrations. At the single-particle level, this is achieved through fluorescence detection, reaching down to single fluorophores. Sensitivity may also be improved by concentrating many particles into a compact cluster, thus "integrating" the signal of many particles. We show how both ways can be combined on an optofluidic chip in a fully planar geometry utilizing counterpropagating liquid-core waveguide modes to form a loss-based optical trap. This all-optical concentrator can increase the concentration of particles by more than 2 orders of magnitude and also provides a convenient, nondispersive means of transport for particle ensembles.
机译:溶液中颗粒的超高灵敏度检测意味着可以在非常低的浓度下进行检测。在单粒子水平上,这是通过荧光检测实现的,甚至可以达到单个荧光团。通过将许多粒子集中到一个紧凑的簇中,从而“整合”许多粒子的信号,也可以提高灵敏度。我们展示了如何使用反向传播的液芯波导模式,以基于损耗的光阱,将两种方式组合在全平面几何形状的光流体芯片上。这种全光聚光器可以将粒子的浓度提高2个数量级以上,并且还为粒子集合体提供了一种方便的,非分散的传输方式。

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