In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy

Izatt JA; Kulkami MD; Yazdanfar S; Barton JK; Welch AJ

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In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy

机译：使用光学相干层析成像技术对皮升血容量进行体内双向彩色多普勒血流成像

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We describe a novel optical system for bidirectional color Doppler imaging of flow in biological tissues with micrometer-scale resolution and demonstrate its use for in vivo imaging of blood flow in an animal model. Our technique, color Doppler optical coherence tomography (CDOCT), performs spatially localized optical Doppler velocimetry by use of scanning low-coherence interferometry. CDOCT is an extension of optical coherence tomography (OCT), employing coherent signal-acquisition electronics and joint time-frequency analysis algorithms to perform flow imaging simultaneous with conventional OCT imaging. Cross-sectional maps of blood flow velocity with <50-mu m spatial resolution and <0.6-mm/s velocity precision were obtained through intact shin in living hamster subdermal tissue. This technology has several potential medical applications. (C) 1997 Optical Society of America.

机译：我们描述了一种新型光学系统，用于双向彩色多普勒成像，具有微米级分辨率的生物组织中的流动，并展示了其在动物模型中对血流进行体内成像的用途。我们的技术，彩色多普勒光学相干断层扫描（CDOCT），通过使用扫描低相干干涉术来执行空间定位的光学多普勒测速。 CDOCT是光学相干断层扫描（OCT）的扩展，它采用相干信号采集电子设备和联合时频分析算法来执行与常规OCT成像同时的流成像。通过完整的胫骨在活的仓鼠皮下组织中获得具有<50-μm空间分辨率和<0.6-mm / s速度精度的血流速度的横截面图。该技术具有多种潜在的医学应用。（C）1997年美国眼镜学会。

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《Optics Letters》 |1997年第18期|共3页
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Izatt JA; Kulkami MD; Yazdanfar S; Barton JK; Welch AJ;
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1. In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy [J] . Izatt JA, Kulkami MD, Yazdanfar S, Optics Letters . 1997,第18期

机译：使用光学相干层析成像技术对皮升血容量进行体内双向彩色多普勒血流成像
2. Three-dimensional reconstruction of blood vessels from in vivo color Doppler optical coherence tomography images. [J] . Kehlet Barton-J, Izatt JA, Kulkarni MD, Dermatology: international journal for clinical and investigative dermatology . 1999,第4期

机译：从体内彩色多普勒光学相干断层扫描图像三维重建血管。
3. Measurement of absolute blood flow velocity and blood flow in the human retina by dual-beam bidirectional Doppler Fourier-domain optical coherence tomography [J] . WerkmeisterR.M., DragostinoffN., PalkovitsS., Investigative ophthalmology & visual science . 2012,第10期

机译：双光束双向多普勒傅里叶域光学相干断层扫描技术测量人视网膜中的绝对血流速度和血流
4. In vivo Doppler flow imaging of picoliter blood volumes using optical coherence tomography [C] . Izatt, J.A., Kulkarni, . 2001

机译：使用光学相干层析成像技术对皮升血容量进行体内多普勒血流成像
5. Noninvasive microstructural and velocity imaging in humans by color Doppler optical coherence tomography. [D] . Yazdanfar, Siavash. 2003

机译：彩色多普勒光学相干断层扫描技术在人体中进行非侵入性微结构和速度成像。
6. Response of Retinal Blood Flow to Systemic Hyperoxia as Measured with Dual-Beam Bidirectional Doppler Fourier-Domain Optical Coherence Tomography [O] . René M. Werkmeister, Stefan Palkovits, Reinhard Told, -1

机译：作为测量与双光束双向多普勒傅里叶域光学相干断层扫描视网膜的血液流向全身高氧的反应
7. In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography [O] . Joseph A. Izatt, Manish D. Kulkarni, Siavash Yazdanfar, 1997

机译：使用光学相干层析成像技术对皮升血容量进行体内双向彩色多普勒血流成像

In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy

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