Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media

Liu Q; Ramanujam N

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Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media

机译：使用倾斜光纤探头进行混浊介质深度敏感荧光光谱法可行性的实验证明

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An angled fiber-optic probe that facilitates depth-sensitive fluorescence measurements was developed for enhancing detection of epithelial precancers. The probe was tested on solid, two-layered phantoms and proved to be effective in selectively detecting fluorescence from different layers. Specifically, a larger illumination angle provides greater sensitivity to fluorescence from the top layer as well as yielding an overall higher fluorescence signal. Monte Carlo simulations of a theoretical model of the phantoms demonstrate that increasing the illumination angle results in an increased excitation photon density and, thus, in increased fluorescence generated in the top layer. (C) 2004 Optical Society of America.

机译：开发了一种有助于深度敏感荧光测量的倾斜光纤探头，用于增强对上皮癌前病变的检测。该探针在坚固的两层体模上进行了测试，并被证明可有效地选择性检测来自不同层的荧光。具体地说，较大的照明角度可提高对顶层荧光的敏感度，并产生总体较高的荧光信号。幻影理论模型的蒙特卡洛模拟表明，增加照明角度会导致激发光子密度增加，并因此导致在顶层产生的荧光增加。（C）2004年美国眼镜学会。

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《Optics Letters》 |2004年第17期|共3页
作者
Liu Q; Ramanujam N;
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原文格式 PDF
正文语种 eng
中图分类光学;
关键词
AUTOFLUORESCENCE; MICROSCOPY; COLLAGEN; SPECTRA;

机译：自荧光;显微镜;胶原;光谱;

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专利

1. Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media [J] . Liu Q, Ramanujam N Optics Letters . 2004,第17期

机译：使用倾斜光纤探头进行混浊介质深度敏感荧光光谱法可行性的实验证明
2. Effects of fiber-optic probe design and probe-to-target distance on diffuse reflectance measurements of turbid media: an experimental and computational study at 337 nm [J] . Thanassis Papaioannou, Norris W. Preyer, Qiyin Fang, Applied Optics . 2004,第14期

机译：光纤探头设计和探头到目标的距离对混浊介质漫反射率测量的影响：337 nm的实验和计算研究
3. Effects of fiber-optic probe design and probe-to-target distance on diffuse reflectance measurements of turbid media: an experimental and computational study at 337 nm [J] . Thanassis Papaioannou, Norris W. Preyer, Qiyin Fang, Applied optics . 2004,第14期

机译：光纤探头设计和探头到目标的距离对混浊介质漫反射率测量的影响：337 nm的实验和计算研究
4. Determination of Fluorescein, Rhodamine 6G and Rhodamine B in Turbid Solution by Variable-angle synchronous fluorescence spectroscopy [C] . Fang Qian, Yao Qun Li, Xian Zhi Huang Xiamen international symposium on spectrochemistry progress prospects : Abstracts book . 1996

机译：变角同步荧光光谱法测定混浊溶液中的荧光素，若丹明6G和若丹明B
5. Development of fiber-optic probe designs and methods for depth-sensitive optical measurements. [D] . Liu, Quan. 2005

机译：开发用于深度敏感光学测量的光纤探头设计和方法。
6. Autofluorescence and diffuse reflectance spectroscopy of oral epithelial tissue using a depth-sensitive fiber-optic probe [O] . Richard A. Schwarz, Wen Gao, Dania Daye, -1

机译：使用深度敏感型光纤探头的口腔上皮组织的自发荧光和漫反射光谱
7. Autofluorescence and diffuse reflectance spectroscopy of oral epithelial tissue using a depth-sensitive fiber-optic probe [O] . Richard A. Schwarz, Wen Gao, Dania Daye, 2008

机译：使用深度敏感光纤探针进行口腔上皮组织的自发荧光和漫反射光谱

Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media

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