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Individualized treatment in stage IVC nasopharyngeal carcinoma

机译:IVC分期的鼻咽癌的个体化治疗

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摘要

The stage IVC nasopharyngeal carcinoma is a catch-all entity covering minute solitary metastasis to bulky disseminated disease. Prognosis varies greatly within this stage group. A subset of patients with oligometastases may benefit from aggressive local ablative therapy. Meanwhile, in multiple metastatic diseases, customizing conventional cytotoxics basing on individual tumor characteristics and previous chemotherapy responses can be a new direction to improve therapeutic results. Prognostic models built on clinical features and genomic profiles can be utilized to stratify different risk groups and tailor therapy schemes.
机译:IVC分期的鼻咽癌是一个万能的实体,涵盖了微小的单发转移到大块散播性疾病。在该阶段组中,预后差异很大。一部分低聚转移患者可能会从积极的局部消融治疗中受益。同时,在多种转移性疾病中,根据个体肿瘤特征和以往的化疗反应定制常规的细胞毒性药物可能是改善治疗效果的新方向。建立在临床特征和基因组概况上的预后模型可用于对不同的风险组进行分层并制定治疗方案。

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