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首页> 外文期刊>Oral oncology >Surgery alone provides long-term survival rates comparable to those of surgery plus postoperative radiotherapy for patients with adenoid cystic carcinoma of the palate.
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Surgery alone provides long-term survival rates comparable to those of surgery plus postoperative radiotherapy for patients with adenoid cystic carcinoma of the palate.

机译:单独手术可为with上腺样囊性癌患者提供与手术加术后放疗相当的长期存活率。

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摘要

We compared the outcomes and rates of survival provided by surgery alone and surgery combined with postoperative radiotherapy for patients with adenoid cystic carcinoma of the palate (ACP), a rare, low-grade malignant tumor arising within the salivary glands. Fifty-eight patients with ACP were included in this retrospective study. ACP at stages T(1), T(2), T(3,) and T(4) was found in 11, 32, 5, and 10 patients, respectively. The patients were treated with surgery alone or underwent surgery combined with postoperative radiotherapy. The 5, 10, and 15year survival rates were 75%, 37.5%, and 25%, respectively, among the 24 patients who underwent surgery alone. These were not significantly different from the rates of 70.6%, 35.3%, and 20.8%, respectively, among the 34 patients who underwent surgery plus postoperative radiotherapy (P=0.21). The 5 and 10year survival rates were significantly greater among patients receiving 60Gy of radiotherapy than those among patients receiving <60Gy of radiotherapy (83.3% and 45.8% vs. 40.0% and 10.0%, respectively) (P=0.04). ACP exhibited good long-term survival rates when treated with surgery alone. Addition of postoperative radiotherapy at doses of 60Gy had no effect on survival, but postoperative radiotherapy at doses of <60Gy reduced survival. Recurrence within the palate was the main cause of treatment failure.
机译:我们比较了单独手术和手术联合术后放疗对for涎腺腺样囊性癌(ACP)患者(唾液腺中罕见的一种低度恶性肿瘤)的治疗效果和生存率。这项回顾性研究纳入了58例ACP患者。在分别为11、32、5和10位患者的T(1),T(2),T(3)和T(4)阶段发现了ACP。患者接受单独手术治疗或接受手术结合术后放疗。在仅接受手术的24例患者中,其5年,10年和15年生存率分别为75%,37.5%和25%。在接受手术加术后放疗的34例患者中,这些比率与分别为70.6%,35.3%和20.8%的比率没有显着差异(P = 0.21)。接受60Gy放射治疗的患者的5年和10年生存率明显高于接受<60Gy放射治疗的患者(分别为83.3%和45.8%,分别为40.0%和10.0%)(P = 0.04)。仅通过手术治疗时,ACP表现出良好的长期生存率。术后60Gy剂量的放疗对生存期无影响,但<60Gy剂量的放疗后生存期降低。 pa内复发是治疗失败的主要原因。

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