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Targeting of chemoprevention to high-risk potentially malignant oral lesions: Challenges and opportunities

机译:化学预防针对高风险的潜在恶性口腔病变:挑战和机遇

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摘要

Worldwide, oral cancer is responsible for 170,000 deaths per year. Intervention to prevent this disease is a long sought after goal. Chemoprevention studies have focused on clinicopathological features of potentially malignant lesions (PML) in an effort to prevent their progression to cancer. However, prediction of future behavior for such lesions is difficult and remains a major challenge to such intervention.
机译:在世界范围内,口腔癌每年导致170,000例死亡。预防这种疾病的干预是一个长期追求的目标。化学预防研究集中于潜在恶性病变(PML)的临床病理特征,以防止其发展为癌症。然而,预测此类病变的未来行为是困难的,并且仍然是此类干预的主要挑战。

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