BDNF mediated TrkB activation contributes to the EMT progression and the poor prognosis in human salivary adenoid cystic carcinoma

Jia Sen; Wang Weixi; Hu Zhiqiang; Shan Chun; Wang Lei; Wu Baolei; Yang Zihui; Yang Xinjie; Lei Delin

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BDNF mediated TrkB activation contributes to the EMT progression and the poor prognosis in human salivary adenoid cystic carcinoma

机译：BDNF介导的TrkB激活有助于人唾液腺腺样囊性癌的EMT进展和不良预后

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Background: The aim of the present study was to investigate whether the expression of Brain-Derived Neurotrophic Factor (BDNF) and its receptor Tropomyosin-related kinase B (TrkB) is correlated with the clinical progression of salivary adenoid cystic carcinoma (SACC) and whether the BDNF/TrkB axis is associated with the induction of epithelial-mesenchymal transition (EMT) in SACC cells.

机译：背景：本研究的目的是研究脑源性神经营养因子（BDNF）及其受体促肌球蛋白相关激酶B（TrkB）的表达是否与涎腺腺样囊性癌（SACC）的临床进展相关。 BDNF / TrkB轴与SACC细胞中上皮-间质转化（EMT）的诱导有关。

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《Oral oncology》 |2015年第1期|共7页
作者
Jia Sen; Wang Weixi; Hu Zhiqiang; Shan Chun; Wang Lei; Wu Baolei; Yang Zihui; Yang Xinjie; Lei Delin;
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正文语种 eng
中图分类耳鼻咽喉科学;
关键词
Salivary adenoid cystic carcinoma; EMT; BDNF; TrkB;

机译：涎腺腺样囊性癌;EMT;BDNF;TrkB;

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专利

1. BDNF mediated TrkB activation contributes to the EMT progression and the poor prognosis in human salivary adenoid cystic carcinoma [J] . Jia Sen, Wang Weixi, Hu Zhiqiang, Oral oncology . 2015,第1期

机译：BDNF介导的TrkB激活有助于人唾液腺腺样囊性癌的EMT进展和不良预后
2. NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma [J] . Huan Li, Zihui Yang, Weiqi Wang, Journal of Cancer . 2019,第24期

机译：NT-3 / TRKC轴有助于对人唾液腺腺样囊性癌的危及侵袭和预后不良
3. EGFR activation induced Snail-dependent EMT and myc-dependent PD-L1 in human salivary adenoid cystic carcinoma cells [J] . Wang Yang, Hu Jingzhou, Wang Yanan, Cell cycle . 2018,第12期

机译：EGFR激活诱导人唾液腺腺样囊性癌细胞中的蜗牛依赖的EMT和MYC依赖性PD-L1
4. Clinical and Radiological Study of Adenoid Cystic Carcinoma in Salivary gland, Sinonasal Tract and Nasopharyngeal [C] . Bo-Hong SHI, Yong-Mei HUANG, Tao QIN International Conference on Biological Sciences and Technology . 2016

机译：唾液腺腺体囊性癌，SinoNasal道和鼻咽癌的临床和放射学研究
5. Identification and Characterization of Neural-like Cancer Stem Cells in Salivary Adenoid Cystic Carcinoma. [D] . Panaccione, Alexander Colin. 2016

机译：唾液腺样囊性癌中神经样癌干细胞的鉴定与表征。
6. NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma [O] . Huan Li, Zihui Yang, Weiqi Wang, 2019

机译：NT-3 / TrkC轴有助于人唾液腺腺样囊性癌的神经周浸润和不良预后。
7. NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma [O] . Huan Li, Zihui Yang, Weiqi Wang, 2019

机译：NT-3 / TRKC轴有助于对人唾液腺腺样囊性癌的危及侵袭和预后不良

BDNF mediated TrkB activation contributes to the EMT progression and the poor prognosis in human salivary adenoid cystic carcinoma

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