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首页> 外文期刊>Osteoarthritis and cartilage >MRI of bone marrow edema-like signal in the pathogenesis of subchondral cysts.
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MRI of bone marrow edema-like signal in the pathogenesis of subchondral cysts.

机译：软骨下囊肿发病机理中的骨髓水肿样信号的MRI。

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OBJECTIVE: To determine if a relationship exists between bone marrow edema-like signal and subchondral cysts on magnetic resonance imaging (MRI). DESIGN: Retrospective cohort of 32 patients with two sequential knee MRI. Patients with acute trauma, infection, neoplasm, or osteonecrosis were excluded. The degree of osteoarthritis was assessed using an adaptation of the Baltimore Longitudinal Study of Aging (BLSA) scale. Initial and follow-up exams were reviewed for presence, location, size and changes of marrow edema-like signal, subarticular cysts and cartilage abnormality. All locations in the knee were aggregated for analysis with descriptive statistics. RESULTS: The mean time interval between exams was 17.52 months (range 2.1-40.1 months). There were 23 cysts: 11 (47.8%) new, 6 (26.1%) increased size, 1 (4.4%) decreased size, and 5 (21.7%) no change in pre-existing lesions. Cysts always arose from regions of marrow edema-like signal. There were 68 subarticular areas of marrow edema-like signal: 16 (23.5%) new, 23 (33.8%) increased size, 17 (25%) decreased size, 11 (16.2%) resolved and 1 (1.5%) no change in pre-existing lesion. Marrow edema-like signal size always changed with cyst development: increased in 6/11 (54.5%), decreased in 2/11 (18.1%) and resolved in 3/11 (27.2%). Change in cyst size was always accompanied by a change in edema-like signal size. An MRI visible cartilage abnormality was adjacent to 87% (20/23) of cysts. The mean BLSA score changed from 2.6 to 3.6 indicating an overall progression of osteoarthritis. CONCLUSION: Subchondral cysts develop in pre-existing regions of subchondral bone marrow edema-like signal.
机译：目的：通过磁共振成像（MRI）确定骨髓水肿样信号与软骨下囊肿之间是否存在关系。设计：回顾性队列32例患者，两次连续膝关节MRI检查。排除有急性创伤，感染，肿瘤或骨坏死的患者。骨关节炎的程度使用巴尔的摩纵向纵向研究（BLSA）量表的改编进行评估。对初次和随访检查进行了检查，以检查是否存在，位置，大小和骨髓水肿样信号，关节下囊肿和软骨异常的变化。将膝盖的所有位置汇总在一起，以进行描述性统计分析。结果：两次检查之间的平均时间间隔为17.52个月（范围2.1-40.1个月）。有23个囊肿：新发11个（47.8％），增大的大小为6个（26.1％），减小的大小为1个（4.4％），并且已有的病变没有变化的5个（21.7％）。囊肿总是从骨髓水肿样信号区域产生的。共有68个关节下区域出现骨髓水肿样信号：新生16个（23.5％），大小增加23（33.8％），大小减少17（25％），分辨出来11（16.2％），有1个（1.5％）无变化既往病灶。骨髓水肿样信号的大小总是随囊肿的发展而变化：在6/11（54.5％）中增加，在2/11（18.1％）中减少，在3/11（27.2％）中消失。囊肿大小的改变总是伴随着水肿样信号大小的改变。 MRI可见的软骨异常邻近于87％（20/23）的囊肿。 BLSA的平均评分从2.6变为3.6，表明骨关节炎总体发展。结论：软骨下囊肿出现在软骨下骨髓水肿样信号的既存区域。

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