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首页> 外文期刊>Osteoarthritis and cartilage >The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review.
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The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review.

机译：骨关节炎定义对患病率和发病率估计的影响：系统评价。

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OBJECTIVE: To understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints. METHOD: A systematic review was carried out in PUBMED and SCOPUS databases comprising the date of publication period from January 1995 to February 2011. We attempted to summarise data on the incidence and prevalence of OA according to different methods of assessment: self-reported, radiographic and symptomatic OA (clinical plus radiographic). Prevalence estimates were combined through meta-analysis and between-study heterogeneity was quantified. RESULTS: Seventy-two papers were reviewed (nine on incidence and 63 on prevalence). Higher OA prevalences are seen when radiographic OA definition was used for all age groups. Prevalence meta-analysis showed high heterogeneity between studies even in each specific joint and using the same OA definition. Although the knee is the most studied joint, the highest OA prevalence estimates were found in hand joints. OA of the knee tends to be more prevalent in women than in men independently of the OA definition used, but no gender differences were found in hip and hand OA. Insufficient data for incidence studies didn't allow us to make any comparison according to joint site or OA definition. CONCLUSIONS: Radiographic case definition of OA presented the highest prevalences. Within each joint site, self-reported and symptomatic OA definitions appear to present similar estimates. The high heterogeneity found in the studies limited further conclusions.
机译：目的：根据病例定义，了解膝，髋和手关节中骨关节炎（OA）的患病率和发病率估算值的差异。方法：在PUBMED和SCOPUS数据库中进行了系统的回顾，包括1995年1月至2011年2月的发布日期。我们尝试根据不同的评估方法总结关于OA发生率和患病率的数据：自我报告，放射照相和症状性OA（临床加影像学检查）。通过荟萃分析合并患病率估计值，并量化研究之间的异质性。结果：审查了72篇论文（发病率9例，患病率63篇）。当对所有年龄组使用射线照相OA定义时，OA患病率较高。患病率荟萃分析显示，即使在每个特定关节中，并且使用相同的OA定义，研究之间的异质性也很高。尽管膝关节是研究最多的关节，但手部关节关节炎的患病率最高。独立于所使用的OA定义，女性的膝关节OA倾向于比男性更普遍，但髋部和手部OA没有发现性别差异。发病率研究的数据不足，无法根据联合部位或OA定义进行任何比较。结论：OA的放射线影像学病例定义具有最高的患病率。在每个关节部位，自我报告的和有症状的OA定义似乎提供了相似的估计。研究中发现的高度异质性限制了进一步的结论。

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