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首页> 外文期刊>Osteoarthritis and cartilage >Knee arthroscopic surgery is beneficial to middle-aged patients with meniscal symptoms: A prospective, randomised, single-blinded study
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Knee arthroscopic surgery is beneficial to middle-aged patients with meniscal symptoms: A prospective, randomised, single-blinded study

机译：膝关节镜手术对半月板症状的中年患者有益：一项前瞻性，随机，单盲研究

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Objective: There is no evidence that a knee arthroscopy is more beneficial to middle-aged patients with meniscal symptoms compared to other treatments. This randomised controlled trial aimed to determine whether an arthroscopic intervention combined with a structured exercise programme would provide more benefit than a structured exercise programme alone for middle-aged patients with meniscal symptoms that have undergone physiotherapy. Method: 150 out of 179 eligible patients, aged 45 to 64 (mean:54±5), symptom duration more than 3 months and standing X-ray with Ahlb?ck grade 0, were randomised to: (1) a physiotherapy appointment within 2 weeks of inclusion that included instructions for a 3-month exercise programme (non-surgery group); or (2) the same as (1) plus, within 4 weeks of inclusion, knee arthroscopy for resection of any significant meniscal injuries (surgery group). The primary outcome was change in pain at 12 months, assessed with the Knee Injury and Osteoarthritis Outcome Score (KOOSPAIN). Results: In the Intention-To-Treat analysis, pain at 12 months was significantly lower in the surgery than in the non-surgery group. The change in KOOSPAIN was significantly larger in the surgery than in the non-surgery group (between-group difference was 10.6 points of change; 95% CI: 3.4 to 17.7, P=0.004). The As-Treated analysis results were consistent with the Intention-To-Treat analysis results. Conclusion: Middle-aged patients with meniscal symptoms may benefit from arthroscopic surgery in addition to a structured exercise programme. Patients' age or symptom history (i.e., mechanical symptoms or acute onset of symptoms) didn't affect the outcome. Trial registration: NCT01288768.
机译：目的：没有证据表明与其他治疗方法相比，膝关节镜检查对具有半月板症状的中年患者更有益。这项随机对照试验旨在确定关节镜干预与结构化锻炼计划相结合是否比单独的结构化锻炼计划为经过物理治疗的半月板症状的中年患者提供更多的益处。方法：在179名合格患者中，将150名年龄在45至64岁（平均：54±5），症状持续时间超过3个月且站立X线检查的Ahlb？ck等级为0的患者随机分为：（1）入选2周，其中包括3个月锻炼计划的说明（非手术组）;或（2）与（1）相同，另加4周内膝关节镜检查以切除任何严重的半月板损伤（手术组）。主要结果是根据膝关节损伤和骨关节炎结果评分（KOOSPAIN）评估的12个月时疼痛的变化。结果：在意向治疗分析中，与非手术组相比，手术后12个月的疼痛明显降低。与非手术组相比，手术中KOOSPAIN的变化明显更大（组间差异为10.6个变化点; 95％CI：3.4至17.7，P = 0.004）。处理后的分析结果与意图治疗分析结果一致。结论：半月板症状的中年患者除了有组织的锻炼计划外，还可从关节镜手术中受益。患者的年龄或症状史（即机械症状或症状的急性发作）不影响预后。试用注册：NCT01288768。

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