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首页> 外文期刊>Sarcoidosis, vasculitis, and diffuse lung diseases: official journal of WASOG >Splenectomy in sarcoidosis: indications, complications, and long-term follow-up.
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Splenectomy in sarcoidosis: indications, complications, and long-term follow-up.

机译：结节病的脾切除术：适应症，并发症和长期随访。

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BACKGROUND: Management of splenic enlargement due to sarcoidosis consists of primarily medical therapy with prednisone, methotrexate or antimalarial drugs. Splenectomy is the last resort because of the concern about complications of surgery. AIM: This study was conducted to explore indications for splenectomy in sarcoidosis and to assess if complications associated with splenic removal were unacceptable. METHODS/RESULTS: 13 sarcoidosis patients had their spleens removed for one or more of the following four reasons: (1) Massive splenomegaly; (2) Severe hypersplenism; (3) Need for excluding lymphoma or malignancy; and (4) Precaution against splenic rupture. All patients received strict prophylactic protocol and were followed over a period ranging from 1 to 30 years. CONCLUSION: In this long term follow-up study none of the thirteen patients developed serious infections or sepsis. No deaths occurred that might be related to splenectomy.
机译：背景：结节病引起的脾肿大的治疗主要包括泼尼松，甲氨蝶呤或抗疟疾药物的药物治疗。由于担心手术并发症，脾切除术是最后的选择。目的：进行这项研究以探讨结节病脾切除术的适应症，并评估与脾切除相关的并发症是否不可接受。方法/结果：13例结节病患者的脾脏被切除是由于以下四个原因中的一个或多个：（1）脾肿大; （二）严重脾气虚; （3）需要排除淋巴瘤或恶性肿瘤; （4）预防脾破裂。所有患者均接受了严格的预防措施，并在1至30年内进行了随访。结论：在这项长期的随访研究中，十三名患者均未出现严重感染或败血症。没有发生可能与脾切除有关的死亡。

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