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首页> 外文期刊>Sarcoidosis, vasculitis, and diffuse lung diseases: official journal of WASOG >Sarcoidosis presenting in patients older than 50 years.
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Sarcoidosis presenting in patients older than 50 years.

机译：结节病存在于50岁以上的患者中。

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BACKGROUND: Sarcoidosis occurs most often between 20 and 40 years of age, but also presents in children and older adults. Newly diagnosed sarcoidosis in older patients has received little attention. In order to characterize sarcoidosis in older patients, the clinical, radiographic and laboratory features of sarcoidosis presenting in patients aged 50 or older were compared to patients whose sarcoidosis was diagnosed at an earlier age. METHODS: The medical records of 181 consecutive patients with sarcoidosis were reviewed. They were divided into 92 patients diagnosed at 50 years of age or older (group A), and 89 whose diagnosis preceded age 50 (group B). RESULTS: Comparison of group A with group B revealed that the two groups were similar with regard to race, gender, smoking habits, common presenting symptoms, organ system involvement, pulmonary function data, radiographic stage, PPD status, and laboratory values. At the time of diagnosis, most patients in both groups presented with either respiratory symptoms or asymptomatic chest roentgenogram abnormalities. The most prevalent pulmonary function abnormality was reduced diffusing capacity in both groups. Most patients exhibited either stage I or II chest roentgenograms. Organ systems most commonly involved included lung, lymph nodes, and skin. CONCLUSION: Sarcoidosis presents with similar clinical features whether diagnosed in young adults or in patients over the age of 50. The diagnosis of sarcoidosis should be considered in patients presenting over age 50 with characteristic signs and symptoms including chest radiographic evidence of mediastinal lymphadenopathy.
机译：背景：结节病最常发生在20至40岁之间，但也存在于儿童和老年人中。新诊断的老年患者结节病很少受到关注。为了表征老年患者的结节病，将50岁或50岁以上患者结节病的临床，影像学和实验室特征与早年诊断为结节病的患者进行了比较。方法：回顾了181例结节病患者的病历。他们分为92位诊断为50岁或50岁以上的患者（A组）和89位诊断为50岁之前的患者（B组）。结果：A组与B组的比较显示，两组在种族，性别，吸烟习惯，常见症状，器官系统受累，肺功能数据，影像学分期，PPD状态和实验室检查值方面相似。在诊断时，两组中的大多数患者均出现呼吸道症状或无症状的胸部X线照片异常。两组中最普遍的肺功能异常是扩散能力降低。大多数患者表现出I期或II期胸部X线胸片。最常见的器官系统包括肺，淋巴结和皮肤。结论：结节病的临床特征无论是在年轻成年人中还是在50岁以上的患者中均得到诊断。结节病的诊断应考虑到50岁以上，具有特征性体征和症状的患者，包括胸部纵隔淋巴结肿大的影像学证据。

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