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首页> 外文期刊>Sarcoidosis, vasculitis, and diffuse lung diseases: official journal of WASOG >Impact of pain in a Dutch sarcoidosis patient population.
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Impact of pain in a Dutch sarcoidosis patient population.

机译：疼痛对荷兰结节病患者群体的影响。

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BACKGROUND AND AIM: Although pain is prevalent in sarcoidosis, this has never been studied systematically. The aim of the present study was to evaluate the presence and impact of pain in sarcoidosis. METHODS: Members from the Dutch Sarcoidosis Society without co-morbidity (n = 821) participated in this study. The World Health Organisation Quality of Life assessment instrument (WHOQOL-100) was completed, as well as a symptom inventory questionnaire addressing the presence of various categories of pain, i.e., muscle pain, chest pain, abdominal pain, arthralgia, and/or headache. RESULTS: Pain was reported by 594 patients (72.4%). Arthralgia was experienced most frequently (53.8%), followed by muscle pain (40.2%), headache (28.0%) and chest pain (26.9%). The number of types of pain a patient was suffering from (ranging from 0-5) was related to the WHOQOL- 100 Pain and Discomfort scale (r = 0.49, p < 0.001). Patients with more types of pain had lower quality of life (QOL). In addition, the total amount of experienced pain categories was associated with the WHOQOL-100 domain Level of Independence (r = -O.43, p < 0.001), and the facet Energy and Fatigue (r = -0.38, p < 0.001). The number of types of pain was predicted by using analgesics, psychologicaleurological medication, NSAIDs, being female, indicating to feel tired, more negative feelings and less energy (F(7.635) = 35.2, p < 0.001; R2 = 27.9%). CONCLUSIONS: Pain appeared to be a major problem in sarcoidosis, especially arthralgia. Although negative feelings and fatigue were related to pain, it could not fully explain pain. Future studies are needed to address mechanisms of pain, pain behaviour, and the best therapeutic approach to pain in sarcoidosis.
机译：背景与目的：尽管结节病普遍存在疼痛，但尚未对其进行系统的研究。本研究的目的是评估结节病中疼痛的存在和影响。方法：荷兰结节病学会无合并症的患者（n = 821）参加了这项研究。完成了世界卫生组织的生活质量评估工具（WHOQOL-100），以及针对各种疼痛类别的症状清单调查表，这些疼痛类别包括肌肉痛，胸痛，腹痛，关节痛和/或头痛。结果：594例患者报告疼痛（72.4％）。关节痛的发生率最高（53.8％），其次是肌肉疼痛（40.2％），头痛（28.0％）和胸痛（26.9％）。患者所遭受的疼痛类型（0-5）与WHOQOL-100疼痛和不适量表相关（r = 0.49，p <0.001）。疼痛类型更多的患者的生活质量（QOL）较低。此外，经历过的疼痛类别的总数与WHOQOL-100域的独立性水平相关（r = -O.43，p <0.001），以及方面的能量和疲劳（r = -0.38，p <0.001） 。通过使用止痛药，心理/神经疗法药物，NSAIDs（女性）来预测疼痛的类型，表明感到疲倦，负感更多，精力更少（F（7.635）= 35.2，p <0.001; R2 = 27.9％） 。结论：疼痛似乎是结节病，尤其是关节痛的主要问题。尽管消极的感觉和疲劳与疼痛有关，但不能完全解释疼痛。需要进一步的研究来解决疼痛，疼痛行为以及结节病疼痛的最佳治疗方法。

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