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首页> 外文期刊>Sarcoidosis, vasculitis, and diffuse lung diseases: official journal of WASOG >Sarcoidosis and dermatomyositis in a patient with hemoglobin SC. A case report and literature review.
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Sarcoidosis and dermatomyositis in a patient with hemoglobin SC. A case report and literature review.

机译：血红蛋白SC患者的结节病和皮肌炎。病例报告和文献复习。

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摘要

Although sarcoidosis has occasionally been associated with hemoglobinopathies, its association with dermatomyositis is extremely rare. A 24 y/o African American male with hemoglobin SC disease developed proximal weakness. He had heliotrope rash, muscle weakness, elevated serum CK, myositis by EMG, and no malignancy. A muscle biopsy confirmed dermatomyositis. Two years later, he was hospitalized with constitutional and respiratory symptoms and parotid enlargement. Chest X-ray and CT scan showed diffuse micronodular infiltration in both lungs and mediastinal lymphadenopathy. A transbronchial lung biopsy revealed non-caseating granulomata consistent with sarcoidosis. AFB and fungal stains and cultures were negative. Thus, in this case, sarcoidosis developed after or in association with dermatomyositis. A review of world's literature showed five other non-identical cases of dermatomyositis associated with sarcoidosis.
机译：尽管结节病有时与血红蛋白病有关，但与皮肌炎的联系却极为罕见。患有血红蛋白SC病的24岁非裔美国男性出现近端无力。他患有天芥子皮疹，肌肉无力，血清CK升高，肌电图引起的肌炎，无恶性肿瘤。肌肉活检证实为皮肌炎。两年后，他因体质和呼吸系统症状以及腮腺肿大入院。胸部X线和CT扫描显示肺和纵隔淋巴结肿大均弥漫性微结节浸润。经支气管肺活检发现非干酪样肉芽肿与结节病一致。 AFB和真菌染色和培养均为阴性。因此，在这种情况下，结节病在皮肌炎之后或与之相关。对世界文学的回顾表明，还有另外五例与结节病相关的皮肌炎病例。

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