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首页> 外文期刊>Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery >Botulinum toxin treatment for symptomatic Frey's syndrome.
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Botulinum toxin treatment for symptomatic Frey's syndrome.

机译：肉毒杆菌毒素治疗症状性Frey综合征。

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摘要

Gustatory sweating, or Frey's syndrome, usually occurs after surgery or trauma to the parotid gland as a result of inappropriate parasympathetic cholinergic innervation of cutaneous sympathetic receptors. Numerous medical and surgical treatments have been proposed to prevent or treat this condition. The results, overall, have been unsatisfactory. Botulinum toxin is a relatively new treatment modality for Frey's syndrome. We review the literature and present our experience with 7 patients successfully treated with intradermal injections of botulinum toxin (Botox). Our technique and dosing are described. In all treated patients gustatory sweating ceased in the area injected with botulinum toxin. In 6 patients, symptoms reappeared, and additional injections were needed up to 4 times, at 6- to 8-month intervals. All patients now have been free of symptoms for a long period of time (mean 12.1 months). We strongly recommend intradermal injections of botulinum toxin as a safe, efficacious treatment for gustatory sweating.
机译：由于皮肤交感受体不适当地副交感神经对胆碱能的支配，通常在手术或腮腺创伤后发生排汗或弗雷氏综合症。已经提出了许多医学和外科治疗方法来预防或治疗这种状况。总体而言，结果并不令人满意。肉毒杆菌毒素是弗雷氏综合症的一种相对较新的治疗方法。我们回顾了文献，并介绍了我们的经验，这些患者经皮内注射肉毒杆菌毒素（Botox）成功治疗了7例患者。描述了我们的技术和剂量。在所有接受治疗的患者中，注射肉毒杆菌毒素的区域不再出现味觉出汗。在6例患者中，症状再次出现，并且需要在6至8个月的间隔内最多再注射4次。现在，所有患者都已长期没有症状（平均12.1个月）。我们强烈建议皮内注射肉毒杆菌毒素作为一种安全有效的味觉出汗治疗方法。

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