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Old and new aspects of middle turbinate histopathology.

机译:中鼻甲的新旧方面病理组织学。

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摘要

OBJECTIVE: To study the histology of the normal and pathologic middle turbinate (MT). STUDY DESIGN: Nonrandomized, controlled study. SUBJECTS AND METHODS: Qualitative and quantitative assessment of soft tissue and bony elements of 14 normal and 10 chronic rhinosinusitis (CRS) MT samples (patients' mean CT score, 6.5 +/- 6.7). A comparison with 14 normal inferior turbinate (IT) samples was accomplished. Quantitative assessment was limited to the lateral mucosal layer (LML). RESULTS: The thickness of the LML was significantly greater in pathologic MT than in normal MT (P = 0.002). Except for veins that underwent significant increase (P = 0.036), other soft tissue constituents of the pathologic MT did not change significantly. Glands were more abundant in normal MT and veins in normal IT (P < 0.001, P = 0.001, respectively). Qualitative assessment showed larger veins in the normal IT compared with the normal MT. Inflammatory cell infiltrate, edema, and fibrosis were found in CRS. None of our MT bones exhibited osteomyelitic changes. CONCLUSIONS: The different proportion of glands suggests varied functional roles for both the MT and IT. The significant involvement of the MT in the inflammatory process of CRS and the relatively small size and paucity of veins with relatively little effect on nasal airflow justify partial excision of the MT.
机译:目的:研究正常和病理性中鼻甲的组织学。研究设计:非随机对照研究。研究对象和方法:定性和定量评估14例正常和10例慢性鼻-鼻窦炎(CRS)MT样本的软组织和骨成分(患者的平均CT评分为6.5 +/- 6.7)。与14个正常下鼻甲(IT)样品进行了比较。定量评估仅限于外侧粘膜层(LML)。结果:病理性MT的LML厚度明显大于正常MT(P = 0.002)。除静脉显着增加(P = 0.036)外,病理性MT的其他软组织成分均无明显变化。正常MT和正常IT中的静脉中腺体更为丰富(分别为P <0.001,P = 0.001)。定性评估显示,正常IT中的静脉比正常MT大。在CRS中发现炎症细胞浸润,水肿和纤维化。我们的MT骨骼均未显示出骨髓变性。结论:不同比例的腺体提示MT和IT均具有不同的功能角色。 MT大量参与CRS的炎症过程以及相对较小的静脉和较小的静脉,而对鼻气流的影响相对较小,这证明了MT的部分切除是合理的。

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