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首页> 外文期刊>Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery >Association of obstructive sleep apnea and auditory dysfunctions in older subjects.
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Association of obstructive sleep apnea and auditory dysfunctions in older subjects.

机译：老年患者阻塞性睡眠呼吸暂停与听觉功能障碍的关联。

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OBJECTIVE: Determine the association between obstructive sleep apnea (OSA) and auditory dysfunction in older subjects. STUDY DESIGN: Cross-sectional study. SETTING: Hospital volunteer helpers undergoing questionnaire, morphometry measurement, auditory examinations, and polysomnography between 2008 and 2009. SUBJECTS AND METHODS: In total, 224 subjects older than 50 years were randomly sampled for above evaluation and testing. The effects of OSA on the peripheral auditory function, represented by averaged pure-tone threshold of low frequencies (PTA-low) and high frequencies (PTA-high), and central auditory function, shown by pitch pattern sequence (PPS scores), were analyzed. RESULTS: The mean +/- SD age was 61.2 +/- 6.7 years. OSA was confirmed in 6 of 98 women (6.1%) and 28 of 126 men (22.2%). After adjusting for age, gender, and other variables, OSA did not show a significant positive association with PTA-low or PTA-high for all subjects. Conversely, there was a significant negative association between OSA and PPS scores for all subjects, even after adjusting for age, gender, and other variables. When OSA and central obesity together were taken into account in the multivariate linear regression analysis, OSA still showed significant association with PPS score for all subjects. CONCLUSION: OSA is independently associated with poorer central auditory function in older subjects.
机译：目的：确定老年受试者的阻塞性睡眠呼吸暂停（OSA）与听觉功能障碍之间的关系。研究设计：横断面研究。地点：医院志愿者志愿者在2008年至2009年间接受了问卷调查，形态测量，听觉检查和多导睡眠监测。受试者与方法：总共抽取了224名50岁以上的受试者用于上述评估和测试。 OSA对外周听觉功能的影响以低频（PTA-低频）和高频（PTA-高频）的平均纯音阈值表示，而中枢听觉功能由音高模式序列（PPS评分）表示。分析。结果：+/- SD平均年龄为61.2 +/- 6.7岁。在98名女性中有6名（6.1％）和126名男性中有28名（22.2％）确认了OSA。在调整了年龄，性别和其他变量后，OSA并未显示出与所有受试者的PTA低或PTA高显着正相关。相反，即使调整了年龄，性别和其他变量，所有受试者的OSA和PPS得分之间也存在显着的负相关。当在多元线性回归分析中同时考虑OSA和中心性肥胖时，OSA对于所有受试者仍显示与PPS评分显着相关。结论：OSA与老年受试者的中枢听觉功能较差独立相关。

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