...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery >Patterns of regional metastasis in advanced stage cutaneous squamous cell carcinoma of the auricle.
【24h】

Patterns of regional metastasis in advanced stage cutaneous squamous cell carcinoma of the auricle.

机译：耳廓晚期皮肤鳞状细胞癌的区域转移模式。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To determine patterns of regional metastasis in patients with advanced stage cutaneous squamous cell carcinoma of the auricle. STUDY DESIGN: Case series with chart review. SETTING: University-based tertiary care hospitals. SUBJECTS AND METHODS: We analyzed 41 patients with stage III and IV squamous cell carcinoma of the auricle. RESULTS: The mean age was 74.2 years (range, 20.6-91.7 years). Thirty-five patients (85.4%) were stage IV. Twenty-nine patients (70.7%) had a prior history of nonauricular, nonmelanotic skin carcinoma. Twenty-four patients (58.5%) had regional metastasis to either the cervical or parotid nodal basin. In patients with cervical metastasis, the involvement by level was 6.7% (n = 1), 80.0% (n = 12), 46.6% (n = 7), 13.3% (n = 2), and 40.0% (n = 6), respectively. Of the 6 patients with a level 5 metastasis, 3 had primaries in the preauricular region, 2 had primaries of the auricle, and 1 had a primary of the postauricular region. Occult disease was present in 2 patients (9.1%) with cervical metastasis and in 4 patients (18.2%) with periparotid lymph node metastasis. Perineural invasion was seen in 84.4% of the study population. The recurrence rate was 46.3% (n = 19). The median time to recurrence was 28.3 months. CONCLUSION: Patients with advanced stage auricular cutaneous squamous cell carcinoma have a high rate of regional metastasis and recurrence. When planning neck dissections for these patients, level 5 should be included in the resection. Patients demonstrating locally advanced disease without clinical or radiographic evidence of metastasis to the parotid or cervical drainage basin should undergo a parotidectomy and comprehensive neck dissection.
机译：目的：确定耳廓晚期皮肤鳞状细胞癌患者的区域转移模式。研究设计：带有图表审查的案例系列。地点：大学级三级医院。研究对象和方法：我们分析了41例III期和IV期耳廓鳞癌的患者。结果：平均年龄为74.2岁（范围20.6-91.7岁）。 IV期有35例患者（85.4％）。二十九名患者（70.7％）曾有非耳性，非黑色素性皮肤癌的病史。 24例患者（58.5％）转移至宫颈或腮腺淋巴池。宫颈转移患者的受累程度为6.7％（n = 1），80.0％（n = 12），46.6％（n = 7），13.3％（n = 2）和40.0％（n = 6） ）， 分别。在6例转移级别为5的患者中，3例在耳前区原发，2例在耳廓原发，1例在耳廓后原发。隐匿性疾病存在于2例（9.1％）宫颈转移和4例（18.2％）腮腺周围淋巴结转移。在84.4％的研究人群中发现了神经周围浸润。复发率为46.3％（n = 19）。中位复发时间为28.3个月。结论：晚期耳廓皮肤鳞状细胞癌患者具有较高的区域转移和复发率。在为这些患者计划颈部清扫术时，切除应包括5级。表现为局部晚期疾病而无临床或影像学证据转移至腮腺或宫颈引流盆的患者，应进行腮腺切除术和全面的颈部解剖。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号