...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery >Hearing Evaluation in Patients with Exfoliative and Primary Open-Angle Glaucoma.
【24h】

Hearing Evaluation in Patients with Exfoliative and Primary Open-Angle Glaucoma.

机译：剥脱性和原发性开角型青光眼患者的听力评估。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: The aim of this prospective study was to audiologically evaluate consecutive glaucoma patients with or without exfoliation. STUDY DESIGN: Prospective study. SETTING: Glaucoma Unit and Audiology Department at a university hospital. SUBJECTS AND METHODS: Consecutive subjects with exfoliative glaucoma (XFG) or primary open-angle glaucoma (POAG) aged between 50 and 70 years were enrolled. Auditory thresholds at 0.5, 1.0, 2.0, 4.0, and 8.0 Hz were measured bilaterally. Cochlear activity was assessed by recording distortion product otoacoustic emissions (DPOEs). Functional changes in the retrocochlear auditory pathway were evaluated by auditory brainstem responses (ABRs). RESULTS: One hundred and ten patients with XFG and 85 patients with POAG who presented in a glaucoma clinic were investigated. The mean age of study patients was 66.2 +/- 5.6 years; range, 50-70 years). The odds of pathologic ABR central transmission time (interpeak latencies I-III, III-V, and I-V and waves I, III, and V) were 4.34 times higher in patients with XFG than in patients with POAG (95% confidence interval [CI], 2.22-8.49; P < .001). This significant association remained after adjusting for sex and age (odds ratio [OR] 4.12; 95% CI, 2.07-8.22; P < .001). Furthermore, the odds of ABR remained significantly higher in patients with XFG than in patients with POAG (OR 4.36; 95% CI, 2.10-9.06; P < .001) after controlling for systemic diseases (arterial hypertension, coronary heart disease, high cholesterol, and stroke). CONCLUSION: In the first study to compare XFG and POAG monitoring of the peripheral and central auditory pathway, it has been documented that XFG patients show a greater prevalence of retrocochlear pathology.
机译：目的：本项前瞻性研究的目的是从听觉上评估连续性青光眼患者有或没有脱落的情况。研究设计：前瞻性研究。单位：大学医院青光眼科和听觉科。受试者和方法：年龄在50至70岁之间的剥脱性青光眼（XFG）或原发性开角型青光眼（POAG）的连续受试者入选。双向测量0.5、1.0、2.0、4.0和8.0 Hz的听觉阈值。通过记录畸变产物耳声发射（DPOE）评估耳蜗活动。通过听性脑干反应（ABR）评估耳蜗后听觉途径的功能变化。结果：对青光眼门诊的XFG患者110例和POAG患者85例进行了调查。研究患者的平均年龄为66.2±5.6岁;范围（50-70年）。 XFG患者中病理性ABR中心传播时间（峰间潜伏期I-III，III-V和IV以及波I，III和V）的几率比POAG患者高95.34倍（95％置信区间[CI ]，2.22-8.49; P ＜.001）。调整性别和年龄后，这种显着关联仍然存在（优势比[OR] 4.12; 95％CI，2.07-8.22; P <.001）。此外，控制系统性疾病（动脉高血压，冠心病，高胆固醇）后，XFG患者的ABR机率仍显着高于POAG患者（OR 4.36; 95％CI，2.10-9.06; P <.001）。和中风）。结论：在比较XFG和POAG监测外周和中枢听觉通路的第一项研究中，已有文献证明XFG患者的耳蜗后病变发病率更高。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号