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首页> 外文期刊>Otology and neurotology: official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology >Relationship between electrically evoked auditory brainstem response and auditory performance after cochlear implant in patients with auditory neuropathy spectrum disorder
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Relationship between electrically evoked auditory brainstem response and auditory performance after cochlear implant in patients with auditory neuropathy spectrum disorder

机译：听神经病谱系障碍患者人工耳蜗植入后诱发的听觉脑干反应与听觉表现的关系

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Objective: To analyze the pattern of electrically evoked auditory brainstem response (EABR) in auditory neuropathy spectrum disorder (ANSD) patients and to compare their performances with controls. Study Design: Retrospective analysis. Setting: Tertiary referral center. Patients: Eleven patients with ANSD and 9 control subjects with sensorineural hearing loss who did not have neural pathology. Intervention: Diagnostic. Main Outcome Measures: Patients and control subjects each received a cochlear implant (CI) and underwent EABR. EABR threshold, wave V latency, and amplitude were measured as EABR parameters. The results of EABR were categorized as good response, variable response, or no response. Speech perception ability was assessed by the categories of auditory performance (CAP) score. Results: All controls responded to EABR, whereas 6 of the 11 ANSD patients did not respond to EABR. The EABR threshold of the ANSD patients was measured almost within the value of disease controls. However, the Wave V latency displayed variable lengths, and the amplitude showed a wider distribution compared with the value of the disease control. The EABR response group among the ANSD patients showed relatively good performance after CI. In contrast, the nonresponse group demonstrated variable outcomes, although all of them still benefited from CI. Conclusion: The data suggested that all ANSD patients require CI and that EABR results can help establish realistic expectations about future performance. Even if electrical stimulation fails to generate sufficiently synchronized signal for eliciting EABR, CI provides at least partial, measurable auditory benefit in ANSD.
机译：目的：分析听神经病谱障碍（ANSD）患者的电诱发听性脑干反应（EABR）的模式，并将其表现与对照进行比较。研究设计：回顾性分析。地点：第三级转诊中心。患者：11例ANSD患者和9例没有神经病理学的感觉神经性听力减退对照组。干预：诊断。主要结果指标：患者和对照对象均接受人工耳蜗（CI）并接受EABR。测量EABR阈值，V波潜伏期和幅度作为EABR参数。 EABR的结果分为良好响应，可变响应或无响应。语音感知能力通过听觉表现（CAP）评分类别进行评估。结果：所有对照均对EABR有反应，而11名ANSD患者中有6名对EABR无反应。 ANSD患者的EABR阈值几乎在疾病对照的值范围内进行测量。但是，与疾病控制值相比，Wave V潜伏期显示出可变的长度，并且振幅显示出更宽的分布。 CI后，ANSD患者中的EABR反应组表现出相对较好的表现。相比之下，无反应组表现出可变的结局，尽管他们所有人仍然受益于CI。结论：数据表明所有ANSD患者都需要CI，而EABR结果可以帮助建立对未来表现的现实期望。即使电刺激未能产生足以引起EABR的同步信号，CI仍可在ANSD中至少提供部分可测量的听觉益处。

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