...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery >Long-term model of induced canine phonation.
【24h】

Long-term model of induced canine phonation.

机译：诱导犬的发声的长期模型。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Experimental induced phonation in the dog has been used in short-term studies by several investigators and has proved quite useful in laryngeal research. In this study a long-term canine phonation model is described that uses permanently implanted electrodes on the superior and recurrent laryngeal nerves. A serial induced phonation model has not been previously reported and is needed for laryngeal research in which voice results are a primary end point. Inexpensive, reliable, nontoxic electrodes were designed and fabricated. The laryngeal nerves were found to be quite susceptible to injury, necessitating a series of changes in electrode design. Electrode durability and laryngeal nerve viability improved with each design modification; the final design gave a recurrent laryngeal nerve viability rate of 100% at 6 weeks, 83% at 9 weeks, and 73% at 12 weeks. Induced phonation was successfully produced on a repeated basis by stimulating the recurrent laryngeal nerves while passing air through the larynx, in 22 (95.6%) of 23 animals. Stimulation of the superior laryngeal nerves increased vocal fold length and tension but was not required for phonation. Technical aspects of chronic implantation and stimulation of the laryngeal nerves are discussed. The development and successful long-term implantation of electrodes on the laryngeal nerves and their use in repeated induced phonation have not been reported previously.
机译：狗的实验性发声已被一些研究者用于短期研究，并已被证明在喉科研究中非常有用。在这项研究中，描述了一种长期犬的发声模型，该模型在上，反复喉神经上使用永久植入的电极。串行感应发声模型以前尚未见过报道，对于语音结果为主要终点的喉部研究是必需的。设计和制造廉价，可靠，无毒的电极。发现喉神经很容易受伤，需要对电极设计进行一系列更改。每次设计修改都会提高电极的耐用性和喉神经的生存能力;最终设计的喉返神经存活率在6周时为100％，在9周时为83％，在12周时为73％。在23只动物中有22只（95.6％）通过刺激喉返神经同时使空气通过喉头而成功地反复产生诱导发声。刺激喉上神经可增加声带长度和张力，但不需要发声。讨论了慢性植入和刺激喉神经的技术方面。以前尚未报道过电极在喉神经上的开发和成功的长期植入及其在反复诱发声带中的用途。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号