Book Review of Pharmaceutical Process Chemistry for Synthesis, Rethinking the Routes to Scale-Up

Will Watson

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Book Review of Pharmaceutical Process Chemistry for Synthesis, Rethinking the Routes to Scale-Up

机译：用于合成的制药过程化学的书评，重新思考扩大规模的途径

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This book contains 9 chapters and covers the process chemistry used to make 8 of the top 10 selling drugs in the world in 2007-8. The list includes Actos (pioglitazone hydrochloride), Lexapro (escitalopram oxalate), Effexor (veblaxafine hydrochloride), Seroquel (quetiapine hemifumarate), Singulair (montelukast sodium), Prevacid (lansoprazole), Advair Diskus (salmeterol xinafoate), and Lipitor (atorvastatin calcium). The author (formerly with Roche) has only included drugs where he had no previous detailed knowledge of the process chemistry and so deliberately omitted any Roche compounds.

机译：本书包含9章，涵盖了在2007-8年度全球十大畅销药物中有八种用于生产的过程化学。清单包括Actos（盐酸吡格列酮），Lexapro（草酸西酞普兰），Effexor（盐酸维沙沙芬），Seroquel（喹硫平半富马酸盐），Singulair（孟鲁司特钠），Prevacid（兰索拉唑），Advair Diskus（沙美特罗，左辛伐他汀）。作者（以前是Roche的作者）只包括了以前对过程化学没有详细了解的药物，因此特意省略了任何Roche化合物。

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《Organic process research & development》 |2011年第3期|共1页
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Will Watson;
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Book Review of Pharmaceutical Process Chemistry for Synthesis, Rethinking the Routes to Scale-Up

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