Design of Experiments (DoE) and Process Optimization. A Review of Recent Publications

Weissman Steven A.; Anderson Neal G.

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Design of Experiments (DoE) and Process Optimization. A Review of Recent Publications

机译：实验设计（DoE）和过程优化。近期出版物回顾

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Statistical design of experiments (DoE) is a powerful tool for Optimizing processes, and it has been used in many stages of API development. This review summarizes selected publications from Organic Process Research & Development using DoE to show how processes can be optimized efficiently and how DoE findings may be applied to scale-up.

机译：实验统计设计（DoE）是用于优化流程的强大工具，已在API开发的许多阶段中使用。这篇综述总结了使用DoE进行的有机过程研究与开发的精选出版物，以展示如何有效地优化过程以及如何将DoE的发现应用于扩大规模。

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《Organic process research & development》 |2015年第11期|共29页
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Weissman Steven A.; Anderson Neal G.;
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中图分类化学工业;
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入库时间 2022-08-18 14:29:37

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1. Design of Experiments (DoE) and Process Optimization. A Review of Recent Publications [J] . Weissman Steven A., Anderson Neal G. Organic process research & development . 2015,第11期

机译：实验设计（DoE）和过程优化。近期出版物回顾
2. Treatment of simulated industrial wastewater by photo-Fenton process. Part I: The optimization of process parameters using design of experiments (DOE) [J] . Marina Dopar, Hrvoje Kusic, Natalija Koprivanac Chemical engineering journal . 2011,第2期

机译：用光芬顿法处理模拟工业废水。第一部分：使用实验设计（DOE）优化过程参数
3. Design of experiment (DOE) method considering interaction effect of process parameters for optimization of copper chemical mechanical polishing (CMP) process [J] . Nam-Hoon Kim, Min-Ho Choi, Sang-Yong Kim, Microelectronic Engineering . 2006,第3期

机译：考虑工艺参数相互作用影响的实验设计（DOE）方法，用于优化铜化学机械抛光（CMP）工艺
4. Quality-by-Design (QbD): Examining the Impact of Process Variables on Particle Size Distribution for a Pharmaceutical Co-precipitation Process Using Real-Time Lasentec FBRM and PVM Process Monitoring and Design of Experiments (DOE) Approach [C] . Huiquan Wu, Maury White, Mansoor A. Khan American Institute of Chemical Engineers Annual Meeting . 2009

机译：按设计质量（QBD）：使用实时Lasentec FBRM和PVM过程监测和实验设计（DOE）方法，检查工艺变量对药物共沉淀过程的粒度分布的影响
5. Optimization of bio-printing process using Design of Experiments (DOE) and Taguchi Method. [D] . Gonzalez Corrales, Maria Veronica. 2013

机译：使用实验设计（DOE）和田口方法对生物印刷工艺进行优化。
6. Preparation and Optimization of PEGylated Nano Graphene Oxide-Based Delivery System for Drugs with Different Molecular Structures Using Design of Experiment (DoE) [O] . Mohammad Hossain Shariare, Abdullah-Al Masum, Sultan Alshehri, 2021

机译：用实验设计用不同分子结构的药物基于聚氨基纳米石墨烯氧化物递送系统的制备与优化（DOE）
7. Scalable 18F Processing Conditions for Copper-Mediated Radiofluorination Chemistry Facilitate "Design of Experiments" (DoE) Optimization Studies and Afford an Improved Synthesis of 18FOlaparib. [O] . Gregory D. Bowden, Nantanat Chailanggar, Bernd J. Pichler, 2021

机译：可扩展的18F用于铜介导的辐射氟化化学的处理条件促进“实验设计”（DOE）优化研究，得到改善的18F Olaparib的合成。
8. Review of Radial Forging Technology Including Preform Design for Process Optimization. [R] . Domblesky, J. P., Shivpuri, R., Altan, T. 1994

机译：包括工艺优化的瓶坯设计在内的径向锻造技术综述。

Design of Experiments (DoE) and Process Optimization. A Review of Recent Publications

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