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首页> 外文期刊>Scandinavian journal of public health >The Danish National Birth Cohorts Selected scientific contributions within perinatal epidemiology and future perspectives
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The Danish National Birth Cohorts Selected scientific contributions within perinatal epidemiology and future perspectives

机译：丹麦国家出生队列在围产期流行病学和未来观点中的部分科学贡献

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Introduction: In this review a selection of studies published during the period 2002-2010, based on data from the Danish National Birth Cohort linked with other health registers3 is described. Illustrative examples of studies addressing perinatal health outcomes (pregnancy complications and fetal and infant health) of a variety of exposures during pregnancy, as well as examples showing different methodological approaches in design and analyses of the studies, are presented. Research topics: The exposures of interest include alcohol drinking, coffee intake, smoking, use of nicotine substitutes, physical exercise, working conditions, medication and infections during pregnancy, and environmental possible toxins. The study designs cover straightforward cohort analyses, case-control studies and sub-cohort analyses with enriched data collection. Conclusion: So far, the Danish National Birth Cohort has provided important knowledge for evidence-based antenatal care by giving more accurate risk estimates for adverse pregnancy outcomes associated with the exposures of interest. Some new potential hazardous exposures during pregnancy have been identified and others have been put to rest. We believe that this investment in epidemiologic infrastructure was well spent. The existence of the Danish National Birth Cohort together with other cohorts and national registers has given Denmark a leading position in reproductive epidemiology.
机译：简介：在这篇综述中，描述了根据丹麦国家出生队列与其他健康登记册3相关联的数据在2002-2010年期间发表的一些研究。提供了说明性示例研究示例，这些示例针对怀孕期间各种暴露的围产期健康结局（妊娠并发症以及胎儿和婴儿健康），以及在设计和分析研究中显示不同方法学方法的示例。研究主题：感兴趣的接触包括饮酒，咖啡摄入，吸烟，使用尼古丁替代品，体育锻炼，工作条件，药物和怀孕期间的感染以及环境中可能的毒素。研究设计涵盖了直接的队列分析，病例对照研究和具有丰富数据收集的亚队列分析。结论：迄今为止，丹麦国家出生队列通过提供与相关暴露有关的不良妊娠结局的更准确风险估计，为循证产前护理提供了重要知识。已经确定了怀孕期间一些新的潜在危险接触，而其他人则被搁置了。我们认为，在流行病学基础设施方面的投资是合理的。丹麦国家出生队列以及其他队列和国家登记册的存在，使丹麦在生殖流行病学方面处于领先地位。

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