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首页> 外文期刊>Cell and tissue banking: An international journal of banking, engineering & transplantation of cells and tissues >Polarization of human donor corneas
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Polarization of human donor corneas

机译：人类供体角膜极化

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To investigate the de-orientation effect of DSAEK grafts by observing the cross patterns and polarization power of human donor corneas using a polarizing device (Lumaxis(A (R))). Forty human donor corneas were placed in small petri-plates with epithelial side facing up. Polarizing power (arbitrary unit) and crosses were monitored and recorded by the software. The tissue was marked at 'Superior' position to ensure that the base and the polarizer are in alignment with each other after the cut. The anterior lamellar cut was performed using microkeratome. The lenticule was placed back in the same position as marked to mimic the alignment. The tissue was further rotated by 45A degrees ensuring that the base of the cornea and the polarizer were in alignment. The polarization power and 'crosses' were identified at each step. The average of forty corneas from pre-cut to post-45A degrees angular change showed statistically significant difference (p < 0.05) in terms of polarizing power. The cross-shaped pattern deformed and lost the sharpness towards 45A degrees angle. However, multiple variances in terms of 'cross-patterns' were observed throughout the study. Lumaxis(A (R)) was able to determine the worst quality tissue in terms of polarization (no black zone and crosses). Despite the quality of cross pattern which can be used as an additional objective parameter to evaluate the optical properties of the corneal tissue, this preliminary study needs to be further justified in terms of clinical relevance whether polarization changes with oriented or de-oriented grafts have any effects and consequences on the visual acuity.
机译：通过使用偏光装置（Lumaxis（A（R）））观察人类供体角膜的交叉图案和极化功率，来研究DSAEK移植物的去取向效果。将四十个人的供体角膜放置在小培养皿中，上皮侧朝上。偏振功率（任意单位）和十字线由软件监控和记录。将组织标记在“高级”位置，以确保切割后底座和偏振器彼此对齐。使用微型角膜刀进行前板层切割。将小透镜放回与标记相同的位置，以模仿对齐方式。将组织进一步旋转45A度，以确保角膜底部和偏振器对齐。在每个步骤中都确定了极化功率和“十字”。从切角到45A度后的角度变化，四十个角膜的平均值在极化强度方面显示出统计学上的显着差异（p <0.05）。十字形图案变形并向45A度角失去锐度。但是，在整个研究过程中观察到“交叉模式”方面的多个差异。 Lumaxis（A（R））能够确定极化最差质量的组织（无黑色区域和交叉）。尽管十字图案的质量可以用作评估角膜组织光学特性的附加客观参数，但该初步研究仍需要在临床相关性方面进一步合理化，无论是定向或非定向移植物的偏振变化是否具有任何意义。对视敏度的影响和后果。

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