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首页> 外文期刊>Scandinavian journal of clinical and laboratory investigation. >Two weeks of overfeeding with candy, but not peanuts, increases insulin levels and body weight.
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Two weeks of overfeeding with candy, but not peanuts, increases insulin levels and body weight.

机译：两周多吃糖果而不是花生，会增加胰岛素水平和体重。

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OBJECTIVE: To study the effects of snacking based on fast acting carbohydrates (candy) or fat and protein (peanuts) in a prospective randomized, parallel intervention study. METHODS: Basal metabolic rate (BMR) and cardiovascular risk factors were measured before and after hyper-alimentation by addition of 20 kcal/kg (84 kJ/kg) body weight of either candy or roasted peanuts, to the regular caloric intake, for two weeks in healthy subjects. Eleven men and 14 women completed the randomized study. RESULTS: Energy-intake increased similarly in the groups (candy: +46.1+/-35%, peanuts: +46.8+/-28% p=0.96). Body-weight (candy: from 67.3+/-7.6 kg to 68.1+/-7.3 kg, p=0.01, nuts: from 68.7+/-6.1 kg to 69.0+/-5.7 kg p=0.3) and waist circumference increased significantly only in the candy group. At the end of the study LDL cholesterol (candy: 2.6+/-0.4 mmol/l peanuts: 2.1+/-0.4 mmol/l, p=0.005) and ApoB/ApoA-1-ratio (candy: 0.68+/-0.16 peanuts 0.53+/-0.11, p=0.01) were higher in the candy group than in the peanut group. On the other hand, BMR increased only in the peanut group (candy: from 6.657+/-1.1 MJ/24 h to 6.762+/-1.1 MJ/24 h, p=0.3 nuts: from 6.896+/-0.98 MJ/24 h to 7.256+/-1.1 MJ/24 h, p=0.02). CONCLUSION: Two weeks of snacking based on peanuts does not cause the same negative metabolic effects as an isocaloric diet in which the snacking is based on short acting carbohydrates in the form of candy in non-obese healthy subjects.
机译：目的：在一项前瞻性随机平行干预研究中，研究基于速效碳水化合物（糖果）或脂肪和蛋白质（花生）的零食的效果。方法：在正常饮食摄入量中，在正常饮食摄入量中添加20 kcal / kg（84 kJ / kg）体重的糖果或烤花生，以测定高营养前后的基础代谢率（BMR）和心血管危险因素健康受试者数周。 11名男性和14名女性完成了随机研究。结果：各组的能量摄入均类似增加（糖果：+46.1 +/- 35％，花生：+46.8 +/- 28％，p = 0.96）。体重（糖果：从67.3 +/- 7.6千克增加到68.1 +/- 7.3千克，p = 0.01，坚果：从68.7 +/- 6.1千克增加到69.0 +/- 5.7千克p = 0.3）并且腰围明显增加仅在糖果组中。在研究结束时，LDL胆固醇（糖果：2.6 +/- 0.4 mmol / l花生：2.1 +/- 0.4 mmol / l，p = 0.005）和ApoB / ApoA-1-比率（糖果：0.68 +/- 0.16糖果组的花生的花生含量为0.53 +/- 0.11，p = 0.01）高于花生组。另一方面，BMR仅在花生组中增加（糖果：从6.657 +/- 1.1 MJ / 24小时增加到6.762 +/- 1.1 MJ / 24小时，p = 0.3坚果：从6.896 +/- 0.98 MJ / 24 h至7.256 +/- 1.1 MJ / 24 h，p = 0.02）。结论：以花生为基础的零食两周不会产生与等热量饮食相同的负面代谢影响，在零食中，零食以非肥胖健康受试者的糖果形式的短效碳水化合物为基础。

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